ID J2D801_9SPHN Unreviewed; 375 AA.
AC J2D801;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:EJK85934.1};
GN ORFNames=PMI04_00643 {ECO:0000313|EMBL:EJK85934.1};
OS Sphingobium sp. AP49.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1144307 {ECO:0000313|EMBL:EJK85934.1};
RN [1] {ECO:0000313|EMBL:EJK85934.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AP49 {ECO:0000313|EMBL:EJK85934.1};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJK85934.1}.
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DR EMBL; AJVL01000010; EJK85934.1; -; Genomic_DNA.
DR RefSeq; WP_007705697.1; NZ_CP124576.1.
DR AlphaFoldDB; J2D801; -.
DR STRING; 1144307.PMI04_00643; -.
DR PATRIC; fig|1144307.3.peg.603; -.
DR eggNOG; COG0845; Bacteria.
DR OrthoDB; 9774837at2; -.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF4; SLR6042 PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..375
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003746163"
FT DOMAIN 66..285
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 375 AA; 38329 MW; 64E49EBE1C77AE8E CRC64;
MKNLYGLVPL PLMWVIAACS AESANEAQPA AKVASHADEG AIAMSEDQIR SAGIQIGRPV
VGGSGTIELP ATIEGDPQGV QVVSAAIGGR VVALTRNLGQ SVGRGDTLAV IESREAALLN
AGIEAARARL GLANATLARE QRLFAQRVSP EQDLIAARTA AAEARIALRL AQGQMAATGS
GGGLNRVAIT APLSGQVIAR SIVLGQTVAA DTELFRVGNL STVSLSLNLQ PQDAGRVRPG
TPVMVEAPGR KASARISFIS PVLDAGSRLV PAIATLDNKG GQWRVGEAVT ASVALSGNGN
GAARVPSTAV QYVEGRSVVF VRTGTGFRAV PVTVGDMSGD SVIVRSGLKG NERIATINSF
TLKAELGKGE ASHED
//
