ID J2DUZ3_9SPHN Unreviewed; 487 AA.
AC J2DUZ3;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Transcriptional regulator with HTH domain and aminotransferase domain-containing protein {ECO:0000313|EMBL:EJK87002.1};
GN ORFNames=PMI04_00036 {ECO:0000313|EMBL:EJK87002.1};
OS Sphingobium sp. AP49.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1144307 {ECO:0000313|EMBL:EJK87002.1};
RN [1] {ECO:0000313|EMBL:EJK87002.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AP49 {ECO:0000313|EMBL:EJK87002.1};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJK87002.1}.
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DR EMBL; AJVL01000001; EJK87002.1; -; Genomic_DNA.
DR RefSeq; WP_007703906.1; NZ_CP124576.1.
DR AlphaFoldDB; J2DUZ3; -.
DR STRING; 1144307.PMI04_00036; -.
DR PATRIC; fig|1144307.3.peg.13; -.
DR eggNOG; COG1167; Bacteria.
DR OrthoDB; 9804020at2; -.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:EJK87002.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:EJK87002.1}.
FT DOMAIN 25..93
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT REGION 82..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 487 AA; 52452 MW; A7793BB4F7686291 CRC64;
MSTSFLRPPS LLRLLGAWRA QDSAEPAYRQ LAQALRMLVL DGRIGLNVRL PGERELAAAL
GLSRTTIAAA FDRLRDEGYL ESRQGSGSVT RLPPGRVETP TPDIDGVTGD NLLNWTHAAL
PAAPGVGLAY AHAVEALPAY LGDLGYDPLG LPVLRRAIAA HYERRGCPTD PDQIMITNGA
QQGFSLLLQW LAGPGDRAVI DHPTYHNAIQ ALQRANVVPV PVGLPVHGWD IDAMDAAFRQ
TAPRFAYIIA DFHNPTGRSM DPATRRALVS VAMRTHTPLV VDETMVAMGL DGAPPPPVAC
HDPSGRHVIT LGSASKIFWG GLRVGWIRAD PQTVAALGRI RTTMDMASPV VEQLAVAQLI
DADEGLGPRA AMLRDRRDHL LAQLERHLPH WRVESPAGGL SLWAELPRAE ASALAALAGN
HGVRIAAGPR FGVNGAFERF LRLPFTLPQA QLDMGVARLV EADARLHART PRGRDPLALA
LEADRVI
//
