ID J2K048_FLASC Unreviewed; 451 AA.
AC J2K048;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=UDP-N-acetylmuramate-alanine ligase {ECO:0000313|EMBL:EJL66668.1};
GN ORFNames=PMI10_00246 {ECO:0000313|EMBL:EJL66668.1};
OS Flavobacterium sp. (strain CF136).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1144313 {ECO:0000313|EMBL:EJL66668.1, ECO:0000313|Proteomes:UP000007287};
RN [1] {ECO:0000313|EMBL:EJL66668.1, ECO:0000313|Proteomes:UP000007287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF136 {ECO:0000313|EMBL:EJL66668.1,
RC ECO:0000313|Proteomes:UP000007287};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJL66668.1}.
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DR EMBL; AKJZ01000007; EJL66668.1; -; Genomic_DNA.
DR RefSeq; WP_007803571.1; NZ_AKJZ01000007.1.
DR AlphaFoldDB; J2K048; -.
DR STRING; 1144313.PMI10_00246; -.
DR PATRIC; fig|1144313.4.peg.237; -.
DR eggNOG; COG0773; Bacteria.
DR OrthoDB; 9804126at2; -.
DR Proteomes; UP000007287; Unassembled WGS sequence.
DR GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.90.190.20; Mur ligase, C-terminal domain; 1.
DR Gene3D; 3.40.1190.10; Mur-like, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036565; Mur-like_cat_sf.
DR InterPro; IPR036615; Mur_ligase_C_dom_sf.
DR InterPro; IPR013221; Mur_ligase_cen.
DR InterPro; IPR000713; Mur_ligase_N.
DR PANTHER; PTHR43445:SF3; UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE; 1.
DR PANTHER; PTHR43445; UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE-RELATED; 1.
DR Pfam; PF01225; Mur_ligase; 1.
DR Pfam; PF08245; Mur_ligase_M; 1.
DR SUPFAM; SSF51984; MurCD N-terminal domain; 1.
DR SUPFAM; SSF53623; MurD-like peptide ligases, catalytic domain; 1.
DR SUPFAM; SSF53244; MurD-like peptide ligases, peptide-binding domain; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:EJL66668.1}.
FT DOMAIN 3..102
FT /note="Mur ligase N-terminal catalytic"
FT /evidence="ECO:0000259|Pfam:PF01225"
FT DOMAIN 108..280
FT /note="Mur ligase central"
FT /evidence="ECO:0000259|Pfam:PF08245"
SQ SEQUENCE 451 AA; 50449 MW; 0CB9F0A0AC978D00 CRC64;
MKTHFIAIGG SAMHNLALAL HNKGYQVTGS DDAIFEPSKS RLEKKGILPA EMGWFPEKIT
ADLEAVILGM HAKADNPELL KAQELGLKIY SYPEFLYEQS KNKTRVVIGG SHGKTTITSM
ILHVMHYHNI EVDYMVGAQL EGFDTMVHLT EENDFVVLEG DEYLSSPIDR RPKFHLYQPN
IALISGIAWD HINVFPTYDN YVEQFEIFIG KITNGGILVY NENDPEVKRV AEAATNPIRK
LAYSTPEYTV SDGVTLLKTP EGDMPIEVFG AHNLNNLAGA KWICQNMGVD EADFYEAIAS
FKGASKRLEK IAEGKGKVAY KDFAHSPSKV AATTKAVKEQ YPNRTLVACL ELHTYSSLNA
EFLKEYEGAL EYADVAVVFY SPDAVKIKQL EEVTYEQIAS SFNREDLIIY TNPAEFKEYL
FNLNLHNSAL LLMSSGNYGG LNFDEVKELI N
//
