ID J2LK01_9BURK Unreviewed; 636 AA.
AC J2LK01;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Propionate--CoA ligase {ECO:0000313|EMBL:EJL85543.1};
GN ORFNames=PMI15_01788 {ECO:0000313|EMBL:EJL85543.1};
OS Polaromonas sp. CF318.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Polaromonas.
OX NCBI_TaxID=1144318 {ECO:0000313|EMBL:EJL85543.1, ECO:0000313|Proteomes:UP000007275};
RN [1] {ECO:0000313|EMBL:EJL85543.1, ECO:0000313|Proteomes:UP000007275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF318 {ECO:0000313|EMBL:EJL85543.1,
RC ECO:0000313|Proteomes:UP000007275};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJL85543.1}.
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DR EMBL; AKIV01000051; EJL85543.1; -; Genomic_DNA.
DR RefSeq; WP_007866896.1; NZ_AKIV01000051.1.
DR AlphaFoldDB; J2LK01; -.
DR PATRIC; fig|1144318.3.peg.1731; -.
DR OrthoDB; 9766486at2; -.
DR Proteomes; UP000007275; Unassembled WGS sequence.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR012694; Propion_PrpE.
DR NCBIfam; TIGR02316; propion_prpE; 1.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EJL85543.1}.
FT DOMAIN 4..58
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 60..453
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 517..600
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 636 AA; 69790 MW; 278587F888512A11 CRC64;
MTSYTDFYRQ SIDQPEAFWT EQAKLIDWHK PFTRVCNDDK PPFVQWFEGG QINLCHNAVD
RHLKDRPDQA ALIYVSSETG VEKTYSFKEL HAEVQRMAAS LLAMGVVKGD RVLIYMPMIP
EAAFAMLACA RIGAIHCVVF GGFASGSLAS RIDDATPRVI ISADAGSRGG KVVAYKPLLD
EAIRLAGHQP EAVLLVNRGL APMNIVAGRD LHWETLRAKY MHAQVHCEWL DSSAISYTIY
TSGTTGKPKG VQRDTGGYAV ALAASMKHIF DGRAGETYFS TSDIGWVVGH SYIVYGPLIA
GMATIMYEGL PTQGMDGQPN AAIWWRLVEK YKVTGMFSAP TAVRVLKKQD PGLLKKHDLS
SLRAFYLAGE PLDEPTARWI SEGLNVPIID NYWQTESGWP IITLANAVEK KPSRFGSPGV
PMYGYKVKIL HESTGEELTQ PNEKGVVVIE GPTPPGFMQT IWKDDARFVN TYWKSVPGKM
VYSTFDWGIR DEDGYFFILG RTDDVINVAG HRLGTREIEE SISGHAGVAE VAVIGVADPL
KGQVAMAFAV PKDSSVLMDT AAAMKLEGEI MKRVDGDLGA VARPARVHFV SALPKTRSGK
MLRRAIQAVC EGRDAGDLTT MDDPAALQQI RDRVAG
//
