ID   J2Z5T2_9LACO            Unreviewed;       448 AA.
AC   J2Z5T2;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=Xanthine/uracil permease {ECO:0000313|EMBL:EJN55868.1};
GN   ORFNames=A11Y_12490 {ECO:0000313|EMBL:EJN55868.1};
OS   Loigolactobacillus coryniformis subsp. coryniformis CECT 5711.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Loigolactobacillus.
OX   NCBI_TaxID=1185325 {ECO:0000313|EMBL:EJN55868.1, ECO:0000313|Proteomes:UP000007271};
RN   [1] {ECO:0000313|EMBL:EJN55868.1, ECO:0000313|Proteomes:UP000007271}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT5711 {ECO:0000313|Proteomes:UP000007271};
RA   Rodriguez J.M.;
RT   "Complete Genome Sequence of Lactobacillus coryniformis CECT5711.";
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJN55868.1}.
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DR   EMBL; AKFP01000029; EJN55868.1; -; Genomic_DNA.
DR   AlphaFoldDB; J2Z5T2; -.
DR   STRING; 1185325.A11Y_12490; -.
DR   PATRIC; fig|1185325.3.peg.1341; -.
DR   Proteomes; UP000007271; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR017588; UacT-like.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; TIGR00801; ncs2; 1.
DR   NCBIfam; NF037981; NCS2_1; 1.
DR   NCBIfam; TIGR03173; pbuX; 1.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007271};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        21..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        77..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        105..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        133..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        201..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        242..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        322..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        351..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        381..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        406..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   448 AA;  47686 MW;  D1963C24487A7F29 CRC64;
     MIRSQNMQNK QVVSVSHPKA AALGLQHLLA MYSGSVLVPL LIGGALHFSA SQMTYLVSID
     IFMCGLATLL QIWTNRFVGI GLPVVLGCAV QAVEPLKMIG ERFTIGTMYG AIIAAGAFVF
     LIAGAFSKIK RLFPPLVTGT LITVIGLTLI PVAFTNLGGG DASAKNFGSP DSLAVGFLTV
     LVILAVNVWG VGFIRQIAVL IGLLVGTIVA AFMGMVSLQP VAEASWLHFP QPFYFGAPHF
     EWSSILTMIL VSLVSMVEST GVFFALGDIT NRKIESSDLK KGYRAEALAV MLGGIFNTFP
     YTTFSQNVGL VQLSGIKTRK PIFYSAGFLI LLGLLPKVGA VATIIPTPVL GGAMLVMFGM
     VAIQGIRMLR HVDFHNDKNV LIAALSIGLG LGVSVEPTIF QSLPTTLQLL LGNGIVMASL
     SAVLLNLILR PRQPEAELEE DDGLNEEE
//