ID J3CKT8_9FLAO Unreviewed; 442 AA.
AC J3CKT8;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=3-hydroxy-3-methylglutaryl CoA synthase {ECO:0000313|EMBL:EJL73546.1};
GN ORFNames=PMI13_01502 {ECO:0000313|EMBL:EJL73546.1};
OS Chryseobacterium populi.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=1144316 {ECO:0000313|EMBL:EJL73546.1, ECO:0000313|Proteomes:UP000007509};
RN [1] {ECO:0000313|EMBL:EJL73546.1, ECO:0000313|Proteomes:UP000007509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF314 {ECO:0000313|EMBL:EJL73546.1,
RC ECO:0000313|Proteomes:UP000007509};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. HMG-CoA synthase
CC family. {ECO:0000256|ARBA:ARBA00007061}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJL73546.1}.
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DR EMBL; AKJY01000022; EJL73546.1; -; Genomic_DNA.
DR RefSeq; WP_007842285.1; NZ_AKJY01000022.1.
DR AlphaFoldDB; J3CKT8; -.
DR PATRIC; fig|1144316.3.peg.1507; -.
DR OrthoDB; 9769523at2; -.
DR Proteomes; UP000007509; Unassembled WGS sequence.
DR GO; GO:0004421; F:hydroxymethylglutaryl-CoA synthase activity; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR GO; GO:0010142; P:farnesyl diphosphate biosynthetic process, mevalonate pathway; IEA:InterPro.
DR CDD; cd00827; init_cond_enzymes; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR013746; HMG_CoA_synt_C_dom.
DR InterPro; IPR013528; HMG_CoA_synth_N.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43323; 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE; 1.
DR PANTHER; PTHR43323:SF2; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF08540; HMG_CoA_synt_C; 1.
DR Pfam; PF01154; HMG_CoA_synt_N; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
FT DOMAIN 3..177
FT /note="Hydroxymethylglutaryl-coenzyme A synthase N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF01154"
FT DOMAIN 308..406
FT /note="Hydroxymethylglutaryl-coenzyme A synthase C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08540"
SQ SEQUENCE 442 AA; 50242 MW; AA1DA941C08FA7BA CRC64;
MSFGIEAASY HAPSLYLEIK DLAEKRRIEP AKLEKGLGLH KMGFPDVHED AATFAAEALL
KLINDYTINP KDISRIYLGT ESALDAAKPT ASYAMLMVEE VLEKEFGERC FKNCDVVDMT
FACIGAVDAL HNSLDFVRSN PDKKAVVIAS DYAKYELASS GEYTQGGGAV ALLISANPDL
LEIENQWGVA TESVFDFFKP RRHYQKEDLM NAPEIFPDKI EIFTDEPVFD GQYSNQCYQD
RIREAYDHYK EITGRNQPYK DWKYLIFHLP YAFHGKRVFT ELYSLENGLA YETPEEQKAV
AKSDDYLQFI SEKIEKSQRA SSEIGNMYTA SIFMALLSAL QVAYNENEEL TGSEIGFLGY
GSGSKSKVFS GKISENWKTV VSKWNVFENL NNRIAIDFET YEKLHRKQIA QSINPNYKGF
GLQFIEPENP VLKGARYYHY QS
//
