ID J3CZQ2_9BURK Unreviewed; 1057 AA.
AC J3CZQ2;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Cation/multidrug efflux pump {ECO:0000313|EMBL:EJL81536.1};
GN ORFNames=PMI15_03366 {ECO:0000313|EMBL:EJL81536.1};
OS Polaromonas sp. CF318.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Polaromonas.
OX NCBI_TaxID=1144318 {ECO:0000313|EMBL:EJL81536.1, ECO:0000313|Proteomes:UP000007275};
RN [1] {ECO:0000313|EMBL:EJL81536.1, ECO:0000313|Proteomes:UP000007275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF318 {ECO:0000313|EMBL:EJL81536.1,
RC ECO:0000313|Proteomes:UP000007275};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJL81536.1}.
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DR EMBL; AKIV01000085; EJL81536.1; -; Genomic_DNA.
DR RefSeq; WP_007871490.1; NZ_AKIV01000085.1.
DR AlphaFoldDB; J3CZQ2; -.
DR PATRIC; fig|1144318.3.peg.3250; -.
DR OrthoDB; 9757904at2; -.
DR Proteomes; UP000007275; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF28; BLR2861 PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 550..570
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 872..892
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 899..919
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 925..950
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 971..990
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1002..1028
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1057 AA; 115664 MW; BC2095B0C5DB5651 CRC64;
MQLAEVSIRR PVFATVLSLL IVLIGAVSFN RLAVREYPKI DEPVVTVSVR YAGASAEVIE
SQVTKPLEDS IAGIDAVDVI TSISRADQAQ ISVRFRLEKD ADSAAAEVRD RTSRVRNRLP
QAIEEPVIAK VEADAFPVIQ VAFSSDSLTP LQINDLVNRI VKPRLQTVTG VADVRIFGER
KYAMRIWLDT DKLASYKLTT QDVEDAISRS NLELPAGRIE SQQREFSVTS QTDLVRPAQF
REIVIKNVNG FSVKVRDVAR VEEGAADERT AVRLNGRSAV AVGVIRQATA NPLDLSKGVR
EVFPKLRADL PADMLIDVAN DNSVFIDRSV NNVYHTIAEA IVLVALVIFV FLRTLRASII
PIVTIPVSLI GTFAMMALAG FTINTLTLLA LVLAIGLVVD DAIVMLENIF RHIEEGMDPF
SAGIKGAREI GFAVVTMTAT LVAVYAPLAF TPGRTGRLFV EFALALAGAV VVSGFVALTL
TPMMCTQLLK HNPKPNRFDR YMERALTAIS DRYGAVLRWV VTTRYVPEME EGRRPSLAQR
LKGMALQARW IVIGVMLLSA LAIALVFPGM KQELSPIEDR GVILANVNAP DGATLDYTNR
YAKALEKMGE PFPEFDRIFA NVGNPTVAQA SVVYRTVDWD KRSRSTLDMA RELQPKFNAL
PGVTAFPITP PSLGQGFRER PLNFVIQTSD SYQNLNTVVR QMLEEIAKNP GIVSPDVDLR
LNKPELRIEV ERDKAADLGV SVQVVAKAIE TLLGGRNVTR YKRDAEQYDV IVQTEASGRI
TPENIDRIYV RGRNDAMIPL SALVKVRESV SPRELNHFGQ RRSVSITASL ASDYSLGEAL
KFMDQTAAKV LKTGYSTDLN GTSREFRSSQ GALAIVFVLA LLFIFLVLSA QFESFIDPLV
IMLSVPLSMI GALLALKWSG GSLNVYSQIG LITLVGLITK HGILIVEFTN QLRGQGLEMI
DALVKASAQR LRPIMMTTGA MVLGALPLAL AKGAGAESRI QIGWVIVGGM SLGTLLTVFV
VPTMYTLFAR KAIPGANKAV AKEEPDAHHE HPEYVAK
//
