ID J3DCA0_9BURK Unreviewed; 299 AA.
AC J3DCA0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase {ECO:0000313|EMBL:EJL89006.1};
GN ORFNames=PMI15_00722 {ECO:0000313|EMBL:EJL89006.1};
OS Polaromonas sp. CF318.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Polaromonas.
OX NCBI_TaxID=1144318 {ECO:0000313|EMBL:EJL89006.1, ECO:0000313|Proteomes:UP000007275};
RN [1] {ECO:0000313|EMBL:EJL89006.1, ECO:0000313|Proteomes:UP000007275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF318 {ECO:0000313|EMBL:EJL89006.1,
RC ECO:0000313|Proteomes:UP000007275};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJL89006.1}.
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DR EMBL; AKIV01000024; EJL89006.1; -; Genomic_DNA.
DR RefSeq; WP_007863800.1; NZ_AKIV01000024.1.
DR AlphaFoldDB; J3DCA0; -.
DR PATRIC; fig|1144318.3.peg.705; -.
DR OrthoDB; 4333at2; -.
DR Proteomes; UP000007275; Unassembled WGS sequence.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR015814; Pgluconate_DH_NAD-bd_C.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF09130; DUF1932; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
FT DOMAIN 11..125
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 194..262
FT /note="Phosphogluconate dehydrogenase NAD-binding putative
FT C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09130"
FT ACT_SITE 173
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 299 AA; 31258 MW; 2B5192256C507128 CRC64;
MHTYSLSSMS VGLIGYGEVG KIFAAALQAG GAKAVSTWDR LFSEGQRGTE AGIQRCASLA
DLLQHCELVF SAVTASQTLA VAREAAGLLR PGTVFVDLNS ASPKTKRDGA AAIEAAGGRY
LEAAVMTSVP PYGLRVPMLL GGPHAREMAP VLCAWGLDAK AASSELGTAS AIKMCRSVVI
KGLEAIVVES FTAARAYGVE DEVLASLKET MPGLNWEQQG SYFFERVIRH GQRRSQEMAE
SAATMADVGI GGSMAAAASQ RQGWTAALAR QGVFGASADS WRSRADEILA AVGSSNPQR
//
