ID J3K0E5_COCIM Unreviewed; 630 AA.
AC J3K0E5;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Peptidyl-prolyl cis-trans isomerase-like 1 {ECO:0000256|ARBA:ARBA00040798};
GN ORFNames=CIMG_09917 {ECO:0000313|EMBL:EAS27312.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS27312.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; GG704915; EAS27312.3; -; Genomic_DNA.
DR RefSeq; XP_001238895.2; XM_001238894.2.
DR AlphaFoldDB; J3K0E5; -.
DR STRING; 246410.J3K0E5; -.
DR GeneID; 4557805; -.
DR KEGG; cim:CIMG_09917; -.
DR VEuPathDB; FungiDB:CIMG_09917; -.
DR InParanoid; J3K0E5; -.
DR OMA; GMVEYWR; -.
DR OrthoDB; 275452at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR CDD; cd01927; cyclophilin_WD40; 1.
DR Gene3D; 2.40.100.10; Cyclophilin-like; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR InterPro; IPR020892; Cyclophilin-type_PPIase_CS.
DR InterPro; IPR002130; Cyclophilin-type_PPIase_dom.
DR InterPro; IPR044666; Cyclophilin_A-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR45625; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED; 1.
DR PANTHER; PTHR45625:SF4; PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00160; Pro_isomerase; 1.
DR Pfam; PF00400; WD40; 1.
DR PRINTS; PR00153; CSAPPISMRASE.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50891; Cyclophilin-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00170; CSA_PPIASE_1; 1.
DR PROSITE; PS50072; CSA_PPIASE_2; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:EAS27312.3};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT REPEAT 72..104
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 116..157
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 477..629
FT /note="PPIase cyclophilin-type"
FT /evidence="ECO:0000259|PROSITE:PS50072"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 630 AA; 69889 MW; 212EB1436B548B15 CRC64;
MAETNAAPDG PSNKRSRSQL EEESQENDEV SSSEDDYGPA LPTAQPKKKR RKLPYEKLYI
NALPASPRYS KSLMHKEQLS FVVVTPQTDF LITSSIDGVV KFWKKMAVSV EFVKEFRAHL
GEIKSVNASA DGRSFATAGA DKTVKIFDVV TFDLLSVLNL DFVPGCVCWV HPRGASLPLL
AVSGESANDI HIFDGRGENP TPLHILSSIH RAPVVAMAFN NTYNCVVSAD NKGMVEYWRP
EGTFEKPDGL FDLKSSTDLF AFRKAKSSPV SITFSASGHQ FATFSFPDRQ VRIFDFPTGK
LYRSYDESLT TLTEMQQAGT ALQKLEEVEF GRRMAVERDL QNPVVAPKIN VIFDESGHFV
MYGSILGIKC INTFTNRVVK VFGKDEPFRA LNLAIYQGQP QKKGVVTVSM AASANPLLQE
AEERDPILAC TGFAKVRFYL FTNEIEISKS TRDIQNEKPR HDRDAAQAAA AEKQAEMGTS
AILHTTMGDI HLRLFPSVAP KAVENFVTHA RNGYYNNTIF HRVIRKFMIQ GGDPLGDGTG
GESIWGGEFE DEFSSLKHDK PYTLSMANAG PNTNGSQFFI TTEKTPWLDG HHTIFGRAVK
GLDVVHRIEN VKTHKEKPEV DVKIVSISVS
//
