ID J3K2D6_COCIM Unreviewed; 1010 AA.
AC J3K2D6;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=DDT domain-containing protein {ECO:0000313|EMBL:EAS28242.3};
GN ORFNames=CIMG_09446 {ECO:0000313|EMBL:EAS28242.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS28242.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00475}.
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DR EMBL; GG704915; EAS28242.3; -; Genomic_DNA.
DR RefSeq; XP_001239825.2; XM_001239824.2.
DR AlphaFoldDB; J3K2D6; -.
DR STRING; 246410.J3K2D6; -.
DR GeneID; 4559128; -.
DR KEGG; cim:CIMG_09446; -.
DR VEuPathDB; FungiDB:CIMG_09446; -.
DR InParanoid; J3K2D6; -.
DR OMA; FVEVHCA; -.
DR OrthoDB; 1382023at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:UniProt.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR028942; WHIM1_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR013136; WSTF_Acf1_Cbp146.
DR PANTHER; PTHR32075; ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED; 1.
DR PANTHER; PTHR32075:SF6; ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF10537; WAC_Acf1_DNA_bd; 1.
DR Pfam; PF15612; WHIM1; 1.
DR Pfam; PF15613; WSD; 1.
DR SMART; SM00571; DDT; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS51136; WAC; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00475}; Reference proteome {ECO:0000313|Proteomes:UP000001261}.
FT DOMAIN 22..131
FT /note="WAC"
FT /evidence="ECO:0000259|PROSITE:PS51136"
FT DOMAIN 401..464
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT REGION 277..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 663..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..309
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 477..494
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..524
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..679
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 705..727
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1010 AA; 117205 MW; 235C9E93A4490C75 CRC64;
MVLFKRKPVQ YLPKPTIEDD SSEVWVIPET DEVFTSYEPF LQRMNFYKQK RFICEITGHS
SLTFFEALRS EAEGSREVDN AFPEALKEPV LRKVQFSIVS RIDSLVDQLY EVPLSRAEPN
LKTTVELTFF KDFKQDFYPG ERVTVLLTNG SRLQGVVREK ARFPEICRSD GTLERRASSR
YLVKLTNRQN EEALVDDEHL ARDRKIFTKQ MLRSFIKNTV SRESWNGAPW LVKPHIAEYY
HIDTEVPQHL QYGNKAGKKA KVSADKQEDE KLFGFFASQR PQLKPSTKGQ KAKTPQELEK
AKEEQYEAYR RSLNGNPSFR LPKNDKHRPP PPSEAPVALL PEFSVIINNK LPPSPPPPPP
APIKYPIEDL DIPPTDGARR PSLRFLTNDE TAEKLDLGLK MESVGPLLET WNTLNVYCEV
FQLDSFTFDD FLEAMRFSSD DINCELFTEI HCAVLKILVN SEKDQEGAIQ ISLPAAPEED
SEEESEESEP EPEPEPEPVP TRRTTRSSLA RVEINNTKPP PRSRSTTADI KVHRAAEMFT
EYGWIDRVRK RDFKNGGWEL VMIGLLYRLS SRPRLQKICD EILSHLAPLD AEPTRETAQE
QYSTLNINLR IQALQIICML TLETKAIKNY LEECSNQMTE FRKEKIELQR ARKATLEELR
KLHEERKELE PERPPSPAPE PEEIAESKVP GTEEESEATS ESDEEEESYI GRSLRGGADR
ELERKRRQEE ERLRKELAAK LPKGTKQYQR VLKKIEDLKA KVKAYEADIA VLDNDLREAD
CPRTRVLGKD RFWNRYYWFE RNGMPYEGLP NSSTASAGYA NGRIWVQGPD EIEREGFIDL
PDELNRSYFK EFGMTVAERK RAEEGPTSML NAQEWGYYED PDELDELINW LDSRGVREIK
LRKELQLHRD NIAKYMKNRK EHLSQHASKV ELEEEPPTRM STRTKTYTDY SNFHCLKWKN
STALRDNGHL HIEPERPTKR AKRSMDNARE LKMLNRQGKP LARQGTRYNF
//
