ID J3K4N2_COCIM Unreviewed; 462 AA.
AC J3K4N2;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Amine oxidase {ECO:0000313|EMBL:EAS29284.3};
GN ORFNames=CIMG_08030 {ECO:0000313|EMBL:EAS29284.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS29284.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the beta-cyclopiazonate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00043981}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG704913; EAS29284.3; -; Genomic_DNA.
DR RefSeq; XP_001240867.1; XM_001240866.2.
DR AlphaFoldDB; J3K4N2; -.
DR GeneID; 4559370; -.
DR KEGG; cim:CIMG_08030; -.
DR VEuPathDB; FungiDB:CIMG_08030; -.
DR InParanoid; J3K4N2; -.
DR OMA; AFHAHNS; -.
DR OrthoDB; 1771364at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR Gene3D; 1.10.405.20; -; 1.
DR Gene3D; 3.30.70.1990; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR42923:SF26; FMN REDUCTASE LOT6, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06600)-RELATED; 1.
DR PANTHER; PTHR42923; PROTOPORPHYRINOGEN OXIDASE; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001261};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..462
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003771585"
SQ SEQUENCE 462 AA; 51689 MW; 29FAA469CEC7A41F CRC64;
MASSFVRALG LSMISFLGIS MIFPGGSCCS TCGKHEDITR DVCIIGGGSS GTYAAVRLRD
KGKSVVVIEQ DETLGGHTDT LIDPRTKKAI NFGVAIFDDL DITREYFTRL GIKYKDTFFG
NDPGVKLYAN FQTGKIVDHK TSNMSAALTS YAMQAMKYPE LEKGFIFSDP VPEDLVIPFS
KFVEKYDIGD ALEIIYTYCQ GYGDLLERLT VYVLKTFDLA VLNDLKNGFL NPASGNNNEI
YDKAMEIIGS DVLFKSRVED AERRKDGVKL TVKTPSGRKT IHAKKLIISI PPTLHNLRPF
GLDENEKSIF GQFKTTGYYT SLVRVPGLPK FDSMTNYNPD TPYNLPKLPD IYWITPTIIP
DVYDVKYGSP RALREEDVKK DIIRKLRPFQ DASAKDAEFV AWSSHTPFGA TVSRKAIESG
FYKKLYSLQG RHNTYWTGSA FHAHNSGLLW EYTKNLVDTL GI
//
