ID J3K7R1_COCIM Unreviewed; 334 AA.
AC J3K7R1;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=C2H2 finger domain-containing protein {ECO:0000313|EMBL:EAS30761.3};
GN ORFNames=CIMG_06240 {ECO:0000313|EMBL:EAS30761.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS30761.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; GG704912; EAS30761.3; -; Genomic_DNA.
DR RefSeq; XP_001242344.1; XM_001242343.2.
DR AlphaFoldDB; J3K7R1; -.
DR STRING; 246410.J3K7R1; -.
DR GeneID; 4560846; -.
DR KEGG; cim:CIMG_06240; -.
DR VEuPathDB; FungiDB:CIMG_06240; -.
DR InParanoid; J3K7R1; -.
DR OMA; IFISWID; -.
DR OrthoDB; 103614at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.10.2030; DNA/RNA-binding protein Kin17, conserved domain; 1.
DR InterPro; IPR019447; DNA/RNA-bd_Kin17_WH-like_dom.
DR InterPro; IPR037321; KIN17-like.
DR InterPro; IPR038254; KIN17_WH-like_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR12805:SF0; DNA_RNA-BINDING PROTEIN KIN17; 1.
DR PANTHER; PTHR12805; KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG; 1.
DR Pfam; PF10357; Kin17_mid; 1.
DR Pfam; PF12874; zf-met; 1.
DR SMART; SM01253; Kin17_mid; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001261}.
FT DOMAIN 28..50
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT REGION 153..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..246
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..286
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..325
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 334 AA; 38114 MW; 9C3D5B62C4FA04D1 CRC64;
MPRAEVGSTK FISNKLKSKG LQRLRWYCQV CQRQMRDENG FKCHTQSESH VRQMLLVGED
PKKYIQGYSN DFLRDFIQLL RTSHGEKQVH INHFYQEYIA NKEHIHMNAT KWSSLTEFAK
YLGREGICRV EEGEKGIFIS WIDNSPEALR RQDAIRKRER QDRGDEEREK KLIEDQIKRA
QRDKDATGTT DGDAPEAPKK LQRVEGEKIT LNFASKLTPQ ENSAFSSASE KPDQPKMDHE
SETEKSEIPS SASTPAPAAQ AQKVPIKLGL GSSGSKSKNV FASMSRKTAA TKKADIPPRP
LSAIERVMKE DMERKRAREN SGFKGSTMKR QKIS
//
