ID J3K8T1_COCIM Unreviewed; 609 AA.
AC J3K8T1;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 03-MAY-2023, entry version 45.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:EAS31258.3};
GN ORFNames=CIMG_06737 {ECO:0000313|EMBL:EAS31258.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS31258.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; GG704912; EAS31258.3; -; Genomic_DNA.
DR RefSeq; XP_001242841.1; XM_001242840.2.
DR AlphaFoldDB; J3K8T1; -.
DR STRING; 246410.J3K8T1; -.
DR GeneID; 4561158; -.
DR KEGG; cim:CIMG_06737; -.
DR VEuPathDB; FungiDB:CIMG_06737; -.
DR InParanoid; J3K8T1; -.
DR OMA; RPRYMNP; -.
DR OrthoDB; 5491784at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR003903; UIM_dom.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR47793; HISTONE DEACETYLASE COMPLEX SUBUNIT CTI6; 1.
DR PANTHER; PTHR47793:SF1; HISTONE DEACETYLASE COMPLEX SUBUNIT CTI6; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50330; UIM; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 105..190
FT /note="Zinc finger PHD-type"
FT /evidence="ECO:0000259|SMART:SM00249"
FT REGION 1..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..297
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..384
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 66517 MW; 155C8DE55AF6087B CRC64;
MTPRRSSRAR GSQAPPSAIH SSSSSSITSL GRIERNTRSN NKLSSPRRSS THLSQSVDDA
DARSRHDLPQ TRQRNRGRDD EDTHQPPPAN DEYDEEDGDE EEITRCICGQ QDYPGLPPSS
RETIGRSSLK AGVKEESNQD PSAAASEILS DDAGSLFIQC DSCKVWQHGG CVGIMEEALS
PDEYFCEKCR KDLHRVIVSG NGQKSSQYLP VAGTPSPISS ASSTRDNSRS ARDKKSRDNA
DAPKRRSTMN SREAAYEEEL LRRAIEESKE ESKSIIEETN NRRGKRTRSD SEITKQTAKR
QRTSSPSPSS IVSKQSQSQS QPVSEDEKSR AAVNGNKKTR GIVTRNQREK EAPASEKEPE
KEAEIAGRRK GRSERRKADD SEPEANSPTK NTVNGSVPPQ SAPETPDIPP PTQKPSSRKS
GRPARRGRVG RNQYTRDRDI ANGNGTDNQT NSPRRGQSRD GNGDSPPGNG ANGVHVNGGE
SGKPSRPRYM NPNRTTMNDM RRRVAAILEF ISRMQLEMAA TEENATPHNA AGANGSQAPD
SSTVVAALEG AVVNGNIQAP SVAGSAETTQ ESATPKPKEF KDLSSVEMMD ELTRGLLKWQ
QEFGKYGEK
//
