ID J3K972_COCIM Unreviewed; 180 AA.
AC J3K972;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Thioesterase domain-containing protein {ECO:0000259|Pfam:PF03061};
GN ORFNames=CIMG_06905 {ECO:0000313|EMBL:EAS31426.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS31426.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SIMILARITY: Belongs to the thioesterase PaaI family.
CC {ECO:0000256|ARBA:ARBA00008324}.
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DR EMBL; GG704912; EAS31426.3; -; Genomic_DNA.
DR RefSeq; XP_001243009.2; XM_001243008.2.
DR AlphaFoldDB; J3K972; -.
DR STRING; 246410.J3K972; -.
DR GeneID; 4560915; -.
DR KEGG; cim:CIMG_06905; -.
DR VEuPathDB; FungiDB:CIMG_06905; -.
DR InParanoid; J3K972; -.
DR OMA; QMAMIRG; -.
DR OrthoDB; 1758624at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0047617; F:acyl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd03443; PaaI_thioesterase; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR InterPro; IPR039298; ACOT13.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR003736; PAAI_dom.
DR InterPro; IPR006683; Thioestr_dom.
DR NCBIfam; TIGR00369; unchar_dom_1; 1.
DR PANTHER; PTHR21660:SF9; 4HBT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR21660; THIOESTERASE SUPERFAMILY MEMBER-RELATED; 1.
DR Pfam; PF03061; 4HBT; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261}.
FT DOMAIN 66..143
FT /note="Thioesterase"
FT /evidence="ECO:0000259|Pfam:PF03061"
SQ SEQUENCE 180 AA; 20147 MW; 30CC5A9296CC0C4D CRC64;
MADSEARKKA MQAVQTFLDV YRGLMKENDF KGYDRQLMHD LRLIDAEPTG GALWEMDVTE
HWVNMNGVMH GGAYAVIFDM CTAIAMNPIA RDGFLAGVTR SLNISYLRAI PIGTTVRIRA
NVLQHGKTMT LLRGVMESVD GKTIYATAEH HKVAVDAKPQ HANRLRNYRA QMQNEPSGKL
//
