ID J3KBA5_COCIM Unreviewed; 833 AA.
AC J3KBA5;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=DIL and Ankyrin domain-containing protein {ECO:0000313|EMBL:EAS32385.3};
GN ORFNames=CIMG_03409 {ECO:0000313|EMBL:EAS32385.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS32385.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; GG704916; EAS32385.3; -; Genomic_DNA.
DR RefSeq; XP_001243968.1; XM_001243967.2.
DR AlphaFoldDB; J3KBA5; -.
DR STRING; 246410.J3KBA5; -.
DR GeneID; 4564375; -.
DR KEGG; cim:CIMG_03409; -.
DR VEuPathDB; FungiDB:CIMG_03409; -.
DR InParanoid; J3KBA5; -.
DR OMA; WSQVMYW; -.
DR OrthoDB; 1359946at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR CDD; cd15473; Myo5p-like_CBD_DIL_ANK; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR037986; Myo5p-like_CBD_DIL.
DR PANTHER; PTHR16027; DILUTE DOMAIN-CONTAINING PROTEIN YPR089W; 1.
DR PANTHER; PTHR16027:SF6; DILUTE DOMAIN-CONTAINING PROTEIN YPR089W; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01843; DIL; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM01132; DIL; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS51126; DILUTE; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261}.
FT REPEAT 182..214
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 215..247
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 406..700
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 705..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..39
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 710..729
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..774
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 833 AA; 93774 MW; B51751E4FB9648FB CRC64;
MDQAGPYHEA SSDADIYEPN ELEKPKPRAL PDDLPTSLDD RRSVPTYTAE TEMYDGWQGQ
SQFLTSPVPT KPLTFNLTLN DQTHDDDLGF RTSAYPENGR MEGSDARLME MLAAQAAHRD
VGIAGTDEDD IAADKKLTDE QKRDILQKTL NTAASNGDVE RVKKLLNGEA SRYVDVDLPD
EEGTVPLIYA SCFGHHEVVT ALLEAGAQVD NQDRNRWSAL MWAMTNRHKT IAKVLLDYGA
SPEIRSSSGG TAFDFVQPGT DISNYLQENG YNFGSSGIDN DFYDSGFGHG RFEEEMAENE
IKRRMMMEES AMNLEVDLSS LGLDEKLDAM DDELEDQQEF VWDRCLHDQM FVFQEHELDR
ILDIIITTMT PQRSPSQKPI PANVLFLCAR YAHYHASPEL LSTLLLSATD RINTVVEKHQ
WDMTILAFWI SNATLLLHYL KKDGELVSAT VEFQLHLAEL INDIFILIIR DAERRMDKVF
DNAMLEHETI PGFEDVHFQN EWKLFRSKSK VKPEPLEKRL RPPSPKRRAE ISPRNITSLL
SSTLFVLDLY DVHSVITAQI LSQLFYWLGA ELFNRIMTTR RYLARTKAMQ IRMNVSALED
WARLNNRQPE HYENGSTTCT GESTVEAARK HLEPVVELLQ WLQCFSSLGD DLDSLIATLQ
QLPRLTPIQL LHAVKLYRPE VGEKGLPKSA MKYITSLKDD PYLLYRPTSP KAETTPTSQA
TNAAPSTPTV ATMPGKDGDS AEPATPQTPQ LQPPSTSQPQ QQSPSQASPQ PAISASERTS
LLLDPAMTLP FSLPTSTDML ISYGAGFGGT NRDRERKYIP TVPTEFLARF DRS
//
