ID J3KK68_COCIM Unreviewed; 524 AA.
AC J3KK68;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=Nucleolar protein 56 {ECO:0000256|ARBA:ARBA00040742};
GN ORFNames=CIMG_01897 {ECO:0000313|EMBL:EAS36543.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS36543.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family.
CC {ECO:0000256|ARBA:ARBA00009211}.
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DR EMBL; GG704911; EAS36543.3; -; Genomic_DNA.
DR RefSeq; XP_001248126.1; XM_001248125.2.
DR AlphaFoldDB; J3KK68; -.
DR STRING; 246410.J3KK68; -.
DR GeneID; 4565758; -.
DR KEGG; cim:CIMG_01897; -.
DR VEuPathDB; FungiDB:CIMG_01897; -.
DR InParanoid; J3KK68; -.
DR OMA; DNYMFAK; -.
DR OrthoDB; 5489581at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP58/56_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58; 1.
DR PANTHER; PTHR10894:SF0; NUCLEOLAR PROTEIN 56; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 299..417
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 451..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..524
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 524 AA; 58547 MW; 7C335EE30FA6F1FF CRC64;
MADFMLFEGP MGYSLFKVAH QADTVGNRLK EVQDGMQDLA KFGKMVDLVS FLPFQNNKQA
LGEINDISEG VASEMLVSFL DLNLPKPNKK KHVVLGLSDK ALAGSIKAAF PFVECETGDT
SEIVQDMLRG IRMHAAKLLK QLREGDLNTA QLGLGHAYSR AKVKFSVQRD DNHIIQAIAI
LDQLDKAINT FSMRVREWYS WHFPELIKIV SDNQRYARLA LLIRNKKELT EDKLHDIAAI
VEDDEGIARS VIDAAKHSMG QDISESDMEN VISFAERVVS LATYRKTLHG YLVSKMSVVA
PNLAALIGEV VGARLISHAG SLTNLSKYPA STVQILGAEK ALFRALKTKG NTPKYGLLYH
SSFIGRAGPK NKGRISRFLA NKCSIASRID NFSETPSTKF GDVLRKQVEE RLEFYASGAP
PTKNEVAMKD AMDSLLADLE VDDEDKDVEM EGAADLTEKS QKKKEKKEKK EKKEKKEKEG
KKEKKEKKEK KEKKLKSEEA DADTPKKKRK RDSEVGVTKK KQKS
//
