ID J3KTN6_HUMAN Unreviewed; 177 AA.
AC J3KTN6;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Sorting nexin 11 {ECO:0000313|Ensembl:ENSP00000463076.1};
DE Flags: Fragment;
GN Name=SNX11 {ECO:0000313|Ensembl:ENSP00000463076.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000463076.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000463076.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT human lineage.";
RL Nature 440:1045-1049(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000463076.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; AC006468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; J3KTN6; -.
DR SMR; J3KTN6; -.
DR MassIVE; J3KTN6; -.
DR MaxQB; J3KTN6; -.
DR PeptideAtlas; J3KTN6; -.
DR Antibodypedia; 30244; 152 antibodies from 21 providers.
DR Ensembl; ENST00000582481.1; ENSP00000463076.1; ENSG00000002919.15.
DR UCSC; uc060guq.1; human.
DR HGNC; HGNC:14975; SNX11.
DR VEuPathDB; HostDB:ENSG00000002919; -.
DR GeneTree; ENSGT00940000160113; -.
DR OMA; SCCFIRR; -.
DR ChiTaRS; SNX11; human.
DR Proteomes; UP000005640; Chromosome 17.
DR Bgee; ENSG00000002919; Expressed in oral epithelium and 182 other cell types or tissues.
DR ExpressionAtlas; J3KTN6; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd06898; PX_SNX10; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR043544; SNX10/11.
DR PANTHER; PTHR46209; PX DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46209:SF1; SORTING NEXIN-11; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Proteomics identification {ECO:0007829|EPD:J3KTN6,
KW ECO:0007829|MaxQB:J3KTN6};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 16..132
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT NON_TER 177
FT /evidence="ECO:0000313|Ensembl:ENSP00000463076.1"
SQ SEQUENCE 177 AA; 20478 MW; 686856351CC01E43 CRC64;
MGFWCRMSEN QEQEEVITVR VQDPRVQNEG SWNSYVDYKI FLHTNSKAFT AKTSCVRRRY
REFVWLRKQL QRNAGLVPVP ELPGKSTFFG TSDEFIEKRR QGLQHFLEKV LQSVVLLSDS
QLHLFLQSQL SVPEIEACVQ GRSTMTVSDA ILRYAMSNCG WAQEERQSSS HLAKGDQ
//
