ID J3LZL8_ORYBR Unreviewed; 707 AA.
AC J3LZL8;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Phenylalanine ammonia-lyase {ECO:0000256|RuleBase:RU003955};
DE EC=4.3.1.24 {ECO:0000256|RuleBase:RU003955};
GN Name=102709168 {ECO:0000313|EnsemblPlants:OB04G25930.1};
OS Oryza brachyantha (malo sina).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4533 {ECO:0000313|EnsemblPlants:OB04G25930.1};
RN [1] {ECO:0000313|EnsemblPlants:OB04G25930.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 101232 {ECO:0000313|EnsemblPlants:OB04G25930.1};
RX PubMed=23481403;
RA Chen J., Huang Q., Gao D., Wang J., Lang Y., Liu T., Li B., Bai Z.,
RA Luis Goicoechea J., Liang C., Chen C., Zhang W., Sun S., Liao Y., Zhang X.,
RA Yang L., Song C., Wang M., Shi J., Liu G., Liu J., Zhou H., Zhou W., Yu Q.,
RA An N., Chen Y., Cai Q., Wang B., Liu B., Min J., Huang Y., Wu H., Li Z.,
RA Zhang Y., Yin Y., Song W., Jiang J., Jackson S.A., Wing R.A., Wang J.,
RA Chen M.;
RT "Whole-genome sequencing of Oryza brachyantha reveals mechanisms underlying
RT Oryza genome evolution.";
RL Nat. Commun. 4:1595-1595(2013).
RN [2] {ECO:0000313|EnsemblPlants:OB04G25930.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2013) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-phenylalanine = (E)-cinnamate + NH4(+);
CC Xref=Rhea:RHEA:21384, ChEBI:CHEBI:15669, ChEBI:CHEBI:28938,
CC ChEBI:CHEBI:58095; EC=4.3.1.24;
CC Evidence={ECO:0000256|RuleBase:RU003955};
CC -!- PATHWAY: Phenylpropanoid metabolism; trans-cinnamate biosynthesis;
CC trans-cinnamate from L-phenylalanine: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005138, ECO:0000256|RuleBase:RU003955}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU003955}.
CC -!- SIMILARITY: Belongs to the PAL/histidase family.
CC {ECO:0000256|ARBA:ARBA00007238, ECO:0000256|RuleBase:RU003954}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_006652522.1; XM_006652459.2.
DR AlphaFoldDB; J3LZL8; -.
DR STRING; 4533.J3LZL8; -.
DR EnsemblPlants; OB04G25930.1; OB04G25930.1; OB04G25930.
DR GeneID; 102709168; -.
DR Gramene; OB04G25930.1; OB04G25930.1; OB04G25930.
DR KEGG; obr:102709168; -.
DR eggNOG; KOG0222; Eukaryota.
DR HOGENOM; CLU_014801_3_0_1; -.
DR OMA; NDPLSWG; -.
DR OrthoDB; 355118at2759; -.
DR UniPathway; UPA00713; UER00725.
DR Proteomes; UP000006038; Chromosome 4.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0045548; F:phenylalanine ammonia-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0009800; P:cinnamic acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006559; P:L-phenylalanine catabolic process; IEA:InterPro.
DR CDD; cd00332; PAL-HAL; 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR InterPro; IPR001106; Aromatic_Lyase.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR InterPro; IPR022313; Phe/His_NH3-lyase_AS.
DR InterPro; IPR005922; Phe_NH3-lyase.
DR InterPro; IPR023144; Phe_NH3-lyase_shielding_dom_sf.
DR NCBIfam; TIGR01226; phe_am_lyase; 1.
DR PANTHER; PTHR10362; HISTIDINE AMMONIA-LYASE; 1.
DR PANTHER; PTHR10362:SF42; PHENYLALANINE AMMONIA-LYASE; 1.
DR Pfam; PF00221; Lyase_aromatic; 1.
DR SUPFAM; SSF48557; L-aspartase-like; 1.
DR PROSITE; PS00488; PAL_HISTIDASE; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|RuleBase:RU003954};
KW Phenylpropanoid metabolism {ECO:0000256|ARBA:ARBA00023051,
KW ECO:0000256|RuleBase:RU003955};
KW Reference proteome {ECO:0000313|Proteomes:UP000006038}.
SQ SEQUENCE 707 AA; 75852 MW; F952CE4D43F4DB19 CRC64;
MASQTADAAG FAANDPLSWG KAALEMTGSH LDEVKRMVAQ SREPVVKIEG SSLRVGQVAA
VSAAKDASGV VGDRDEGARP RVKASSEGIL NCIAHGGDIY GVTTGFGGTS HRRTKDGPAL
QVELLRHLNA GIFGNGSDGN TLPSEVSRAA MLVRINTLLQ GYSGIRFEIL EAITKLINTG
VSPCLPLRGT ITASGDLVPL SYIAGLITGR PNALAVTVDG KKVDAAEAFK IAGIQGGFFK
LQPKEGLAIV NGTSVGSALA AMVLYDANVL AVLSEVLSAV FCEVMNGKPE YTDHLTHKLK
HHPGSIEAAA IMEHILAGSA FMPHAQKVNE VDPLLKPKQD RYALRTSPQW LGPQIEVIRA
ATKSIEREVN SVNDNPVIDV HRGKALHGGN FQGTPIGVSM DNTRLAIANI GKLMFAQFSE
LVNEFYNNGL TSNLAGSRNP SLDYGFKGTE IAMASYCSEL QFLANPITNH VQSAEQHNQD
VNSLGLVSAR KTAEAVDILK LMSSTYLVAL CQAVDLRHLE ENLKSAVKNC VTTVAKKVLT
TSSTGGLHSA RFSEKALLTA IDREAVYSYA DDPCSANYPL MTKIRAVLVE HSLANGPAEK
DDGTSVFSKI TAFEEELREA LPREMEAARV AFETGTAPIT NRIKESRSFP LYRFVREELG
CVYLTGEKLK SPGEECNKVF LAISQRKLID PMLECLKEWN GEPLPIC
//
