ID J3NFE9_ORYBR Unreviewed; 1137 AA.
AC J3NFE9;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN Name=102717305 {ECO:0000313|EnsemblPlants:OB12G27070.1};
OS Oryza brachyantha (malo sina).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4533 {ECO:0000313|EnsemblPlants:OB12G27070.1};
RN [1] {ECO:0000313|EnsemblPlants:OB12G27070.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 101232 {ECO:0000313|EnsemblPlants:OB12G27070.1};
RX PubMed=23481403;
RA Chen J., Huang Q., Gao D., Wang J., Lang Y., Liu T., Li B., Bai Z.,
RA Luis Goicoechea J., Liang C., Chen C., Zhang W., Sun S., Liao Y., Zhang X.,
RA Yang L., Song C., Wang M., Shi J., Liu G., Liu J., Zhou H., Zhou W., Yu Q.,
RA An N., Chen Y., Cai Q., Wang B., Liu B., Min J., Huang Y., Wu H., Li Z.,
RA Zhang Y., Yin Y., Song W., Jiang J., Jackson S.A., Wing R.A., Wang J.,
RA Chen M.;
RT "Whole-genome sequencing of Oryza brachyantha reveals mechanisms underlying
RT Oryza genome evolution.";
RL Nat. Commun. 4:1595-1595(2013).
RN [2] {ECO:0000313|EnsemblPlants:OB12G27070.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2013) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+)(out) + K(+)(in) = H(+)(in) + K(+)(out);
CC Xref=Rhea:RHEA:29467, ChEBI:CHEBI:15378, ChEBI:CHEBI:29103;
CC Evidence={ECO:0000256|ARBA:ARBA00033682};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+)(out) + Na(+)(in) = H(+)(in) + Na(+)(out);
CC Xref=Rhea:RHEA:29419, ChEBI:CHEBI:15378, ChEBI:CHEBI:29101;
CC Evidence={ECO:0000256|ARBA:ARBA00033620};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_006664256.1; XM_006664193.2.
DR AlphaFoldDB; J3NFE9; -.
DR STRING; 4533.J3NFE9; -.
DR EnsemblPlants; OB12G27070.1; OB12G27070.1; OB12G27070.
DR GeneID; 102717305; -.
DR Gramene; OB12G27070.1; OB12G27070.1; OB12G27070.
DR KEGG; obr:102717305; -.
DR eggNOG; KOG1965; Eukaryota.
DR HOGENOM; CLU_008625_0_0_1; -.
DR OMA; SICPQKL; -.
DR OrthoDB; 1220385at2759; -.
DR Proteomes; UP000006038; Chromosome 12.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 6.10.140.1330; -; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR018422; Cation/H_exchanger_CPA1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR10110; SODIUM/HYDROGEN EXCHANGER; 1.
DR PANTHER; PTHR10110:SF86; SODIUM_HYDROGEN EXCHANGER 7; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000006038};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 721..824
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 1030..1137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1047..1077
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1137 AA; 126914 MW; 01911F286DAB19E7 CRC64;
MAAPDSEPDD AVLFVGVSLV LGIASRHLLR GTRVPYTIAL LVLGVALGSL EFGTKHSLGK
LGAGIRIWAN INPDLLLAVF LPALLFESSF SMEVHQIKKC MAQMVLLAGP GVILSTFFLG
SALKLTFPYN WNWKTSLLLG GLLSATDPVA VVALLKELGA SKKLSTVIEG ESLMNDGTAI
VVYQLFYRMV LGRTFDAGSI IKFLSEVSLG AVALGLAFGI ASVLWLGFIF NDAIIEIALT
LAVSYIAFFT AQDALEISGV LTVMTLGMFY AAFAKTAFKG DSQQSLHHFW EMVAYIANTL
IFILSGVVIA DGVLENNFHF ERHGASWGFL LLLYVFVQIS RILVVAILYP LLRHFGYGLD
LKEATILVWS GLRGAVALSL SLSVKRASDA VQSYLKPVDG TMFVFFTGGI VFLTLILNGS
TTQFLLHLLG MDRLSATKLR ILNYTKYEML NKALEAFGDL RDDEELGPPA DWVTVKKYIK
CLNDLDDEPV HPHALSDRNG RMHSMNLRDI RVRLLNGVQA AYWGMLEEGR ITQATANILM
RSVDEAMDLV PSQALCDWKG LRSNVHFPNY YRFLQMSRLP RRLITYFTVE RLESGCYICA
AFLRAHRIAR RQLHDFLGDS EVARIVIDES NAEGEEARKF LEDVRVTFPQ VLRVLKTRQV
TYSVLTHLSE YIQNLQKTGL LEEKEMAHLD DALQTDLKKF KRNPPLVKMP RVSDLLNTHP
LVGALPALMR DPLLNSTKET VKVHGTILYR EGSRPTGIWL VSVGVVKWTS QRLSSRHSLD
PIFSHGSTLG LYEVLIGKPY ICEMVTDSVV HCFFIEAEKM EQLLQSDPSI EVFLWQESAL
VVARLMLPMM FEKMATHELR VLITERSTMS IYIKGEEIEI EQNYIGILLE GFLKTKNQTL
ITPPGLLLPS NADLNLFGLE SSAINRIDYC YTAPCYQVEA RARILFVELG RAEVEADLQR
SASLISQTLE LPRTHSKEHS GLLSWPESFR KSRGAHNTAS LAEIRDHPAS FSARALQLSM
YGSMINDMQA GQGERRQWHR HTKSSNSKGH SSSYPRVPSK SSNTQRPLLS VQSEGANMRT
AAPPAEAAGR RRQRQRKAIE EDEDNSSDEE EVIIRVDSPS MLTFRQPSAD HQLPQPK
//
