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Database: UniProt
Entry: J3P4H1_GAGT3
LinkDB: J3P4H1_GAGT3
Original site: J3P4H1_GAGT3 
ID   J3P4H1_GAGT3            Unreviewed;      1607 AA.
AC   J3P4H1;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   31-JUL-2019, entry version 41.
DE   SubName: Full=Dicer-like protein 1 {ECO:0000313|EMBL:EJT74568.1};
GN   Name=20348866 {ECO:0000313|EnsemblFungi:EJT74568};
GN   ORFNames=GGTG_08408 {ECO:0000313|EMBL:EJT74568.1};
OS   Gaeumannomyces graminis var. tritici (strain R3-111a-1) (Wheat and
OS   barley take-all root rot fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Sordariomycetidae; Magnaporthales; Magnaporthaceae;
OC   Gaeumannomyces.
OX   NCBI_TaxID=644352 {ECO:0000313|EMBL:EJT74568.1};
RN   [1] {ECO:0000313|EnsemblFungi:EJT74568, ECO:0000313|Proteomes:UP000006039}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R3-111a-1 {ECO:0000313|EnsemblFungi:EJT74568,
RC   ECO:0000313|Proteomes:UP000006039};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ma L.-J., Dead R., Young S., Zeng Q., Koehrsen M., Alvarado L.,
RA   Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA   Howarth C., Jen D., Larson L., Mehta T., Neiman D., Pearson M.,
RA   Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA   Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT   "The genome sequence of Gaeumannomyces graminis var. tritici strain
RT   R3-111a-1.";
RL   Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EJT74568.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=R3-111a-1 {ECO:0000313|EMBL:EJT74568.1};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Ma L.-J., Dead R., Young S., Zeng Q., Koehrsen M., Alvarado L.,
RA   Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA   Howarth C., Jen D., Larson L., Mehta T., Neiman D., Pearson M.,
RA   Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA   Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RL   Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:EJT74568.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=R3-111a-1 {ECO:0000313|EMBL:EJT74568.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ma L.-J., Dead R., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA   Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.,
RA   Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G.,
RA   Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C.,
RA   Larson L., Lui A., MacDonald P.J.P., Mehta T., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S.,
RA   Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Yandava C.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "Annotation of Gaeumannomyces graminis var. tritici R3-111a-1.";
RL   Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EnsemblFungi:EJT74568}
RP   IDENTIFICATION.
RC   STRAIN=R3-111a-1 {ECO:0000313|EnsemblFungi:EJT74568};
RG   EnsemblFungi;
RL   Submitted (APR-2018) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the helicase family. Dicer subfamily.
CC       {ECO:0000256|PROSITE-ProRule:PRU00657}.
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DR   EMBL; GL385398; EJT74568.1; -; Genomic_DNA.
DR   RefSeq; XP_009224512.1; XM_009226248.1.
DR   STRING; 29850.GGTG_08408T0; -.
DR   EnsemblFungi; EJT74568; EJT74568; GGTG_08408.
DR   GeneID; 20348866; -.
DR   OrthoDB; 1337630at2759; -.
DR   Proteomes; UP000006039; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd00593; RIBOc; 2.
DR   Gene3D; 1.10.1520.10; -; 2.
DR   Gene3D; 3.30.160.380; -; 1.
DR   InterPro; IPR038248; Dicer_dimer_sf.
DR   InterPro; IPR005034; Dicer_dimerisation_dom.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000999; RNase_III_dom.
DR   InterPro; IPR036389; RNase_III_sf.
DR   Pfam; PF03368; Dicer_dimer; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   Pfam; PF00636; Ribonuclease_3; 2.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00535; RIBOc; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF69065; SSF69065; 2.
DR   PROSITE; PS51327; DICER_DSRBF; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS00517; RNASE_3_1; 1.
DR   PROSITE; PS50142; RNASE_3_2; 2.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000006039};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006039};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00657}.
FT   DOMAIN      180    363       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      498    659       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
FT   DOMAIN      700    791       Dicer dsRNA-binding fold.
FT                                {ECO:0000259|PROSITE:PS51327}.
FT   DOMAIN     1143   1252       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   DOMAIN     1303   1466       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   REGION       73     96       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      134    169       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    134    161       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   1607 AA;  179956 MW;  01BF983E72215871 CRC64;
     MVASSRLHSK YHPTPALLSL LHRRPTSASA NNPTHITMDC LLSSLAPTGR CDQIPTSENF
     GAAKAGATQS LRTPLVNNVS GDASEDENQD DDGSLDGRIE LVAGAPSKPR KISEKRRADN
     AIFESWVEKN KVRLSQGSSN AKSNDKAGST ELGSDPTADK PSRSQGMRII EGPREYQIEL
     FERAKQKNTI AVLDTGTGKT LISILLIRHI IEKELETRSQ GKENRATFFL VDKVTLVWQQ
     TKQLHSNLDF AITGIHGDSV THLWNDIEYW QKLRSDNMVI VCTAEILYTC LARGYINMRQ
     INLLVFDEAH HTKKNHPYAR IIKDFYVTEE DPDARPRVLG MTASPFDTKT IHIEKAASEL
     ERLLHSEIAT IADDELLKAI GNRAEERNVP YAFLPHREPT DLCKKLETLL RSHSQFKKAF
     STAKIVASEL GPWCADRLWE LKFQDDSGLE GRAESNSRRE NSEWQMCETD QLGDLREAAL
     IVKNSALGPP QDDGLSSKTL KLLEILEENF CSETSTQCIV FVERRDVAVL LTDLVQNPAM
     SVRFPYLNAA YLIASGRGDS HTSISNKKQE ATVWSFRLRE LNCLFATSIA EEGLDIPGCN
     LVIRFDLHKT TIQYIQSRGR ARMAGSVFIQ MTEMGNQDHM RSWYQHQADE RTMRQFCAAL
     PEDRILQRIG ADVDSALHGD QGQRVYVVPE TGARLTYKHS LNVLAEYVGT LPVNVEGLSF
     GPEYTVIPVI GGFQGEVLLP ESSPLRSATG SIQRSKAVAK CSAAYAMCIS LIEAGYLDAY
     LKSTFRKVLP LMRNARLAVS SKKKAQYDMQ TKPDMWSDLG TASRLFATAL VLTNPEALLQ
     DSRPLLLLTR KPIPQVASIP LFIAKRRRSD VQCIPLPPME TTEAGLLGLS SFTFCIFRDV
     FSKDFDGTAA DLPYFLAPVM KGHEHAFSET VDSHALVDWP AIDAIQTPNA MPDSNSEPDE
     FFQHKFVADP FDGSRKFFMS RVRRDLTPQD KVPEDVPAPA HRSWRTAEHT ILNYSVSLWS
     KSRDAIIPRL RKDAPVVEAE LVSLRRNLLD QNDAETAVPQ RTCFLVLETL QISRLPVEVV
     SMAYNFPAII YRLENNLIAL NCCNLLGLSI RPDLALEAVT KDSDNSDEPD EAPVNFQGGM
     GKNYERLEFL GDCFLKMATT IALFTLMAGD EFEYHVERMT DICNKNLLNV ALDMGLQKYI
     RSKSFNRRTW YPSGLTLLKG KRLEADATHS LGDKSIADVC EALIGAAYLT GRERNSFDMA
     VKAVTLLTRS QTHTMKSFAE YRAAYVKPEW QTVPASRLQL ELARRIKEKM GYEFKDARLL
     RSAFMHPSYP RVYENIPSYQ RLEFLGDALL DMTCIDHLFG RFPDRDPQWL TEHKMAMVSN
     QFYGCLAVEL GFHRHVVCLK TQLQGQIADW VDRLGERRRR AEQAAVDAGR PAADFARNFW
     VDMEHPPKCL PDVLEAYVGA LFVDAGYDYG AVEAFWAEHV RPWFADMAAY DTYSAHHPVT
     HLNSILVHQL GCTHHRLLVR EIADTASGEA VVAGATRVVA ACLVHGEVRC HAASASGRYA
     KLAVARKAIA MFGDMGPAEF RRLTGCDCRP GQDGGLAVEE DDGDERR
//
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