ID J3QRB0_HUMAN Unreviewed; 158 AA.
AC J3QRB0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Nuclear prelamin A recognition factor {ECO:0000313|Ensembl:ENSP00000464124.1};
DE Flags: Fragment;
GN Name=NARF {ECO:0000313|Ensembl:ENSP00000464124.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000464124.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000464124.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT human lineage.";
RL Nature 440:1045-1049(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000464124.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NARF family.
CC {ECO:0000256|ARBA:ARBA00006596}.
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DR EMBL; AC124287; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC132938; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; J3QRB0; -.
DR SMR; J3QRB0; -.
DR MassIVE; J3QRB0; -.
DR MaxQB; J3QRB0; -.
DR PeptideAtlas; J3QRB0; -.
DR Antibodypedia; 33014; 222 antibodies from 27 providers.
DR Ensembl; ENST00000577410.2; ENSP00000464124.1; ENSG00000141562.19.
DR UCSC; uc060mcb.1; human.
DR HGNC; HGNC:29916; NARF.
DR VEuPathDB; HostDB:ENSG00000141562; -.
DR GeneTree; ENSGT00940000153514; -.
DR OMA; IKFCEHY; -.
DR ChiTaRS; NARF; human.
DR Proteomes; UP000005640; Chromosome 17.
DR Bgee; ENSG00000141562; Expressed in left testis and 198 other cell types or tissues.
DR ExpressionAtlas; J3QRB0; baseline and differential.
DR Gene3D; 3.40.50.1780; -; 1.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR PANTHER; PTHR11615:SF124; NUCLEAR PRELAMIN A RECOGNITION FACTOR; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:J3QRB0,
KW ECO:0007829|MaxQB:J3QRB0};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 34..153
FT /note="Iron hydrogenase large subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02906"
FT NON_TER 158
FT /evidence="ECO:0000313|Ensembl:ENSP00000464124.1"
SQ SEQUENCE 158 AA; 17920 MW; 42911DC7DF79AD91 CRC64;
MTAEEGVQLS QQNAKDFFRV LNLNKKCDTS KHKVLVVSVC PQSLPYFAAK FNLSVTDASR
RLCGFLKSLG VHYVFDTTIA ADFSILESQK EFVRRYRQHS EEERTLPMLT SACPGWVRYA
ERVLGRPITA HLCTAKSPQQ VMGSLVKDYF ARQQNLSP
//
