ID J3QS26_HUMAN Unreviewed; 141 AA.
AC J3QS26;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Growth arrest specific 7 {ECO:0000313|Ensembl:ENSP00000464494.1};
DE Flags: Fragment;
GN Name=GAS7 {ECO:0000313|Ensembl:ENSP00000464494.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000464494.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000464494.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT human lineage.";
RL Nature 440:1045-1049(2006).
RN [2] {ECO:0007829|PubMed:19690332}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19690332; DOI=10.1126/scisignal.2000007;
RA Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K.,
RA Rodionov V., Han D.K.;
RT "Quantitative phosphoproteomic analysis of T cell receptor signaling
RT reveals system-wide modulation of protein-protein interactions.";
RL Sci. Signal. 2:RA46-RA46(2009).
RN [3] {ECO:0000313|Ensembl:ENSP00000464494.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC000003; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC005747; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC026591; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC083783; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC107938; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF456243; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF570257; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; J3QS26; -.
DR SMR; J3QS26; -.
DR MassIVE; J3QS26; -.
DR MaxQB; J3QS26; -.
DR PeptideAtlas; J3QS26; -.
DR Antibodypedia; 24803; 496 antibodies from 30 providers.
DR Ensembl; ENST00000578599.5; ENSP00000464494.1; ENSG00000007237.19.
DR UCSC; uc060bfk.1; human.
DR HGNC; HGNC:4169; GAS7.
DR VEuPathDB; HostDB:ENSG00000007237; -.
DR GeneTree; ENSGT00940000156268; -.
DR OMA; NAETTWE; -.
DR ChiTaRS; GAS7; human.
DR Proteomes; UP000005640; Chromosome 17.
DR Bgee; ENSG00000007237; Expressed in cerebellar vermis and 211 other cell types or tissues.
DR ExpressionAtlas; J3QS26; baseline and differential.
DR Gene3D; 2.20.70.10; -; 1.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR Pfam; PF00397; WW; 1.
DR Pfam; PF16623; WW_FCH_linker; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:J3QS26,
KW ECO:0007829|PeptideAtlas:J3QS26};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 13..46
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 30..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 141
FT /evidence="ECO:0000313|Ensembl:ENSP00000464494.1"
SQ SEQUENCE 141 AA; 15525 MW; E6F7CE2CAE1C640C CRC64;
MVPPPPGEES QTVILPPGWQ SYLSPQGRRY YVNTTTNETT WERPSSSPGI PASPGSHRSS
LPPTVNGYHA SGTPAHPPET AHMSVRKSTG DSQNLGSSSP SKKQSKENTI TINCVTFPHP
DTMPEQQLLK PTEWSYCDYF W
//
