ID J4C3Q6_THEOR Unreviewed; 2167 AA.
AC J4C3Q6;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=PHD-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TOT_030000118 {ECO:0000313|EMBL:BAM40856.1};
OS Theileria orientalis strain Shintoku.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=869250 {ECO:0000313|EMBL:BAM40856.1, ECO:0000313|Proteomes:UP000003786};
RN [1] {ECO:0000313|EMBL:BAM40856.1, ECO:0000313|Proteomes:UP000003786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shintoku {ECO:0000313|EMBL:BAM40856.1,
RC ECO:0000313|Proteomes:UP000003786};
RX PubMed=22951932;
RA Hayashida K., Hara Y., Abe T., Yamasaki C., Toyoda A., Kosuge T.,
RA Suzuki Y., Sato Y., Kawashima S., Katayama T., Wakaguri H., Inoue N.,
RA Homma K., Tada-Umezaki M., Yagi Y., Fujii Y., Habara T., Kanehisa M.,
RA Watanabe H., Ito K., Gojobori T., Sugawara H., Imanishi T., Weir W.,
RA Gardner M., Pain A., Shiels B., Hattori M., Nene V., Sugimoto C.;
RT "Comparative genome analysis of three eukaryotic parasites with differing
RT abilities to transform leukocytes reveals key mediators of Theileria-
RT induced leukocyte transformation.";
RL MBio 3:e00204-e00212(2012).
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DR EMBL; AP011948; BAM40856.1; -; Genomic_DNA.
DR RefSeq; XP_009691157.1; XM_009692862.1.
DR STRING; 869250.J4C3Q6; -.
DR EnsemblProtists; BAM40856; BAM40856; TOT_030000118.
DR GeneID; 20715317; -.
DR KEGG; tot:TOT_030000118; -.
DR VEuPathDB; PiroplasmaDB:TOT_030000118; -.
DR eggNOG; ENOG502QYFD; Eukaryota.
DR OrthoDB; 248379at2759; -.
DR Proteomes; UP000003786; Chromosome 3.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15571; ePHD; 2.
DR CDD; cd15522; PHD_TAF3; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 4.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF132; PHD FINGER PROTEIN RHINOCEROS; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 5.
DR SMART; SM00184; RING; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000003786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 902..1012
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 2108..2167
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 629..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 803..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1159..1226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1343..1373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1516..1659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2067..2088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..651
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..842
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1159..1185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1186..1201
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1202..1226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1517..1590
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1591..1611
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1612..1659
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2073..2088
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2167 AA; 247399 MW; F8D60650E24C8441 CRC64;
MSSEPQQSKD TSQEEERFWL DFDRQYFAPP HPSLLMCLKN HIWHSKHISS KIGSYLSSKK
NVKKGAKRRH NLNLRTVKFP LRLLGVDKTN ANDGIFKYFS AASYSNDQIQ VLLENDNVYK
PLVSAKHDTN QRLPTIYSSP LPDAIHLTLY IPPTNPKAKS ETNNTNSEPV VKNHNDDESF
NFVDAFGSVQ LLENDQVPQI ICGPNPTWFT KGRGRFKRGL ELGPRYKKCD KLVKNPHGLL
SDPVWQHFNT NYISNPNTNF FTLPAATASS RKSDDDSEFG DGTDLLNYHS MCELGSCRVD
YSPLLFTFVA SKKSLLCKRC LGFPRISCNL CKSISGNSTA MFSSQYISDE RYHMVYNLVD
LFKLRSTTND TIPSYYLNPY RSSRDHQTYA ITKGEEPEGK EDEDEMQLVH NYVQTLESLN
SVFSSLLDRI VNEYKPDTSR WHDIESKMLQ HYIELYNNKT LDNRYTYSVQ RQSVDVLQLR
LKVLKSSELP GTWTDRALCS ICGTDDDWDD DPILFCDCCY IPMHFCCLGY KPGTLSDVKQ
KLMMNKFQRM NYFNYLINNP DKPAKKFKLE RMESLTDMDD DEWYCPVCNY LMEQLSFLDE
NLVMAIIRTV GGPKNLEQLK LLIQHNSGNA NENEAKEQQD ADSKPKRQKL DPNFKYNLPY
VLGFDYDNPL ERVYISVHPT KAITNTTRVF PENNPNHSTD TGINLERISV VNLYDYRNES
ISYNTNCVMD PRNFCKLLLS KKGLYFEHSF WTLLNTCNLA SIQEYLNYYS MEDLYLARLV
QQDKLIQSVK HYTKKRTTSM NSKLSSRTLS VNSDKEYPQV KKEQENHAKE AEPKKEESRY
DYNSTMNCKN PLKKLYVSIN LRYLSNLPSA TVFSKAAPNL NANVMGKEFR KEDDDVDVVI
KLPVCVFCGF DAYFPGGGPM KRTSNNGTWG HIKCALANDC TIEPEEINYS TFVPKIKALK
CIFCNNYSTS SIQCSYGNCC KAFHVPCSSA SPSCLFTWDT NGKPDVLCPV HSKGLAPTSL
LRKLQLRLMN AKDGKDRDFR DPGSEREQRK GKFGKYFVKA KVKEKDKEKN QEDADKSKEK
ETAKNVVKGT RDVLDTVSIN ENLYLNHFLR PNYSNLTKLL ELMLNEKIGT IFQSNLSSNC
YNKDALMRTT STVSVNSTGL TSLSSVSSNV TSNSKSTNQD DLSSNDDMYK VSDREDDDYV
PSITPKSTNT VRDGSLTPSN VTPNEYKNKD DVAMELDETG DEVLLLKNES ILKDASNILL
GKEQLLNKHK GAVEGRCPLN NIDANNCFWC CLGLDLSYHN RHVFDDKTPS SRSVLSILYN
NNLHNVDVIK TIINSKYDNT YESQKEEDDG LANQPSKKSK KKETAKEKED SSDRELKIPW
NMLSSIIMDN VVDEKINIYI NNDLINNTKL IKKNDSVIQK ISSEALVRLF NTFEPDSTRY
VVRTLFSLLK HIEFINGLDE LYGYNSIYYY SSSGMDSPRV LDSKNGLNIP NLNLNENFAG
ANLNLGNLLG NTKNLSFSRK EKNENSSSKE KNEVKDAKEK SKDRSNGVES DRSSSSKDTD
KSVNSKSSDK PNLKEVKTNK AKENEMNGLR EADRSSNSSR SSSSASKGSK ASWKVKENHD
TNDKVKASTE EPKSEASPAD AKDGKSKADE DKAENEKKSA RQEVYKLLKE VNNVEIIKLD
KALLPSSILR KYVENKKITI CKVCLEFKYI ENDIDVNKRK RNIYNESYRK CKCCNVEVCN
SCLTVARHDF ENLTINTSLI VGDYIGEEID DFYFLCIRCK DLTMSNSIPL LNCALCSRYD
GLMLKVNPKH LTFIPCKTSL WNNYCYVHLI CLEWLFWSKN INNNMRKVNR SQFEQNCNYC
GLLTGATVTC SNSACYSKFH ASCAAFLGCK IDVGKKSENI VGAKRALCLR HTLISICRTS
AAERKFMVAP CYLYEVLVNT NYFATFFKAV YLSPNCINNK PKLTSRFKIK KRSKSLDYKN
SLSMMKMASY INYGLITNKS PQVYEVTITE SVARNRLIQG MNYVFYQKAS INAANLFNGK
DPDPSDCNMR EIKNIINLVR NGILKPIQGS KRGRKPKSLD GSDSDKRHKM PMEDILKYGH
RGVLENGEYY CPICFSIYFE NSPGLPGDDL HWIGCDKCER WFHFVCAGVW VDYRDKDSWF
CYHCDNS
//
