ID J4CCK4_THEOR Unreviewed; 733 AA.
AC J4CCK4;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 28-JUN-2023, entry version 48.
DE SubName: Full=CDC5-like {ECO:0000313|EMBL:BAM39547.1};
GN ORFNames=TOT_010001002 {ECO:0000313|EMBL:BAM39547.1};
OS Theileria orientalis strain Shintoku.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=869250 {ECO:0000313|EMBL:BAM39547.1, ECO:0000313|Proteomes:UP000003786};
RN [1] {ECO:0000313|EMBL:BAM39547.1, ECO:0000313|Proteomes:UP000003786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shintoku {ECO:0000313|EMBL:BAM39547.1,
RC ECO:0000313|Proteomes:UP000003786};
RX PubMed=22951932;
RA Hayashida K., Hara Y., Abe T., Yamasaki C., Toyoda A., Kosuge T.,
RA Suzuki Y., Sato Y., Kawashima S., Katayama T., Wakaguri H., Inoue N.,
RA Homma K., Tada-Umezaki M., Yagi Y., Fujii Y., Habara T., Kanehisa M.,
RA Watanabe H., Ito K., Gojobori T., Sugawara H., Imanishi T., Weir W.,
RA Gardner M., Pain A., Shiels B., Hattori M., Nene V., Sugimoto C.;
RT "Comparative genome analysis of three eukaryotic parasites with differing
RT abilities to transform leukocytes reveals key mediators of Theileria-
RT induced leukocyte transformation.";
RL MBio 3:e00204-e00212(2012).
CC -!- SIMILARITY: Belongs to the CEF1 family.
CC {ECO:0000256|ARBA:ARBA00010506}.
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DR EMBL; AP011946; BAM39547.1; -; Genomic_DNA.
DR RefSeq; XP_009689848.1; XM_009691553.1.
DR AlphaFoldDB; J4CCK4; -.
DR STRING; 869250.J4CCK4; -.
DR EnsemblProtists; BAM39547; BAM39547; TOT_010001002.
DR GeneID; 20713831; -.
DR KEGG; tot:TOT_010001002; -.
DR VEuPathDB; PiroplasmaDB:TOT_010001002; -.
DR eggNOG; KOG0050; Eukaryota.
DR OrthoDB; 131128at2759; -.
DR Proteomes; UP000003786; Chromosome 1.
DR GO; GO:0000974; C:Prp19 complex; IEA:InterPro.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd00167; SANT; 1.
DR CDD; cd11659; SANT_CDC5_II; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR047242; CDC5L/Cef1.
DR InterPro; IPR021786; Cdc5p/Cef1_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR047240; SANT_CDC5L_II.
DR PANTHER; PTHR45885; CELL DIVISION CYCLE 5-LIKE PROTEIN; 1.
DR PANTHER; PTHR45885:SF1; CELL DIVISION CYCLE 5-LIKE PROTEIN; 1.
DR Pfam; PF11831; Myb_Cef; 1.
DR Pfam; PF13921; Myb_DNA-bind_6; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
DR PROSITE; PS50090; MYB_LIKE; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000003786};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 1..49
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 2..53
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 54..107
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 54..103
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT REGION 107..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 449..525
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 613..640
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 387..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 733 AA; 84577 MW; 00F5149C51B9D1BB CRC64;
MFIQIKGGVW KNTEDEVLKA AVMKYGLNNW SRVSSLLVNK SAKQCKARWF EWLDPHIKKT
EWSKEEEEKL LHLAKLFPTQ WRTIGPLIGR TAYQCLQHYE RLLDQAQGRE EDDEFDPRKL
RPGEIDPQLE CKPSRPDAVD MDDDEKEMLA EARARLANTR GKKAKRKARE KALEQSKRIA
ALQKRRELKS AGISVRNFKS KKETIDYEHE IPFEIQPPKG FYPPDKDKPA NLSIKNIEQL
EGIRRDQELE RLRKDDIRKL KRLQSDDTPA AMAIFEKYDK SRSLKNRLVL PEPTMTDEEI
NQIIKMGADV QLLENATNSV VARTPMTSSI MEEARIAAMA NKLQTPLEGE INLPDSSFPV
PQTPAQFQTP NPIKQLMAQT PLSIFGARST SGYTPRPSDT SVYDGASDAD PIGAKARMDM
AKLYVKASLS NLPEPEEQVE ITVPEIESLE SDEVDQDQKE ADMEDLEAQK VRLAKKKMEE
DALQDSEVIK RRLPRPSVFN SIVFVNDLEN TFNESQMAQK QLINEEFLNI LAYDSVKHPI
PHGRPADNYV PREHFDINLL EEARRLIDEE ARLLSAGLGD SNLEMDWKTD NFKYSHLQKR
YMPSEKLTLQ EQRASEETLY REYEKHLENL SKRIKGLENK YAVSTGGYRK REELITKEID
DMYESTGQAM NDLSSFSHME ARERLASSER ISAQLDLLQR EKRLNGKLQV SWPQIHPYFR
NCTLKRLGRD PYV
//
