ID J4DPL4_THEOR Unreviewed; 720 AA.
AC J4DPL4;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=inositol-pentakisphosphate 2-kinase {ECO:0000256|ARBA:ARBA00012023};
DE EC=2.7.1.158 {ECO:0000256|ARBA:ARBA00012023};
DE AltName: Full=Ins(1,3,4,5,6)P5 2-kinase {ECO:0000256|ARBA:ARBA00029574};
GN ORFNames=TOT_030000170 {ECO:0000313|EMBL:BAM40909.1};
OS Theileria orientalis strain Shintoku.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=869250 {ECO:0000313|EMBL:BAM40909.1, ECO:0000313|Proteomes:UP000003786};
RN [1] {ECO:0000313|EMBL:BAM40909.1, ECO:0000313|Proteomes:UP000003786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shintoku {ECO:0000313|EMBL:BAM40909.1,
RC ECO:0000313|Proteomes:UP000003786};
RX PubMed=22951932;
RA Hayashida K., Hara Y., Abe T., Yamasaki C., Toyoda A., Kosuge T.,
RA Suzuki Y., Sato Y., Kawashima S., Katayama T., Wakaguri H., Inoue N.,
RA Homma K., Tada-Umezaki M., Yagi Y., Fujii Y., Habara T., Kanehisa M.,
RA Watanabe H., Ito K., Gojobori T., Sugawara H., Imanishi T., Weir W.,
RA Gardner M., Pain A., Shiels B., Hattori M., Nene V., Sugimoto C.;
RT "Comparative genome analysis of three eukaryotic parasites with differing
RT abilities to transform leukocytes reveals key mediators of Theileria-
RT induced leukocyte transformation.";
RL MBio 3:e00204-e00212(2012).
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DR EMBL; AP011948; BAM40909.1; -; Genomic_DNA.
DR RefSeq; XP_009691210.1; XM_009692915.1.
DR AlphaFoldDB; J4DPL4; -.
DR STRING; 869250.J4DPL4; -.
DR EnsemblProtists; BAM40909; BAM40909; TOT_030000170.
DR GeneID; 20715368; -.
DR KEGG; tot:TOT_030000170; -.
DR VEuPathDB; PiroplasmaDB:TOT_030000170; -.
DR eggNOG; ENOG502QXI1; Eukaryota.
DR OrthoDB; 227351at2759; -.
DR Proteomes; UP000003786; Chromosome 3.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0035299; F:inositol pentakisphosphate 2-kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR InterPro; IPR009286; Ins_P5_2-kin.
DR InterPro; IPR018525; MCM_CS.
DR PANTHER; PTHR14456; INOSITOL POLYPHOSPHATE KINASE 1; 1.
DR PANTHER; PTHR14456:SF2; INOSITOL-PENTAKISPHOSPHATE 2-KINASE; 1.
DR Pfam; PF06090; Ins_P5_2-kin; 1.
DR PROSITE; PS00847; MCM_1; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000003786};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 573..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 720 AA; 83273 MW; 5E76221913B97DA3 CRC64;
MYFVYLTPLG AGNYQYVFRI TNLYNRYNDF NIIDVYDQYR YSSLHFIHKY SQNPVNSGIL
AKIPRYWILK IPKNENIEDY ASRIRFHYQF NSFLNHFNKS INHNLSFENR KGDYIAKLRN
FDENRKQNGL NNIASDVPSK MLCVIERSVS QKLRTMFEEL LIPSGKYAND SNMGPDSNST
VAINGNEKSR TNNEMRKMDR NKMMVFYDDV LEKRYSMEID ANSIEIVDAN DLIDHATESK
AKETLRTKRI FDNDRYEFCS IEEDLFNIDR IIEIGNIGEN DRVNGVGKGG GLESCTKDKG
DVKNVSIEIK LKCGLKNFKK YPSMFEMNQI NKRNVNYIMS NGTSKVRGKH ESHYDPCKFF
ELDRESIREE MIKLMQIPQN NLRMFVNNYQ IAPEELFGSE LKRRVRKGVE ADQASGICCT
DEFSNRRASM EEGGDDLLEL VVRSIVENRK KLVMVSKLQA LAAGQQLVAS ALYSMYSLLL
RMGEFTSGSR ERNRGSTKGR EIERDSVMGK GMELVHLMHI KLTSVLNSER RCSFKTSNAN
MAVHRASNEF NANNHRLFKL LNEVVACLLG SSPSGSGRKN GSDDEENVPL KRSKMGSTAR
NSGIHLLILE DEAIKTIMRT IYYRNKKERV ERGRSIKRGI VSESEVERVR AWISMYLYGR
VAMDLSIIVN ILYSGRKNEP GGYRMLYNKV SFVDLDLKSK DKIYKWAIGR QRHRQIRRAK
//
