ID J4DQ30_THEOR Unreviewed; 580 AA.
AC J4DQ30;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Methylase {ECO:0000313|EMBL:BAM41739.1};
GN ORFNames=TOT_040000121 {ECO:0000313|EMBL:BAM41739.1};
OS Theileria orientalis strain Shintoku.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=869250 {ECO:0000313|EMBL:BAM41739.1, ECO:0000313|Proteomes:UP000003786};
RN [1] {ECO:0000313|EMBL:BAM41739.1, ECO:0000313|Proteomes:UP000003786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shintoku {ECO:0000313|EMBL:BAM41739.1,
RC ECO:0000313|Proteomes:UP000003786};
RX PubMed=22951932;
RA Hayashida K., Hara Y., Abe T., Yamasaki C., Toyoda A., Kosuge T.,
RA Suzuki Y., Sato Y., Kawashima S., Katayama T., Wakaguri H., Inoue N.,
RA Homma K., Tada-Umezaki M., Yagi Y., Fujii Y., Habara T., Kanehisa M.,
RA Watanabe H., Ito K., Gojobori T., Sugawara H., Imanishi T., Weir W.,
RA Gardner M., Pain A., Shiels B., Hattori M., Nene V., Sugimoto C.;
RT "Comparative genome analysis of three eukaryotic parasites with differing
RT abilities to transform leukocytes reveals key mediators of Theileria-
RT induced leukocyte transformation.";
RL MBio 3:e00204-e00212(2012).
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DR EMBL; AP011949; BAM41739.1; -; Genomic_DNA.
DR RefSeq; XP_009692040.1; XM_009693745.1.
DR AlphaFoldDB; J4DQ30; -.
DR EnsemblProtists; BAM41739; BAM41739; TOT_040000121.
DR GeneID; 20716217; -.
DR KEGG; tot:TOT_040000121; -.
DR VEuPathDB; PiroplasmaDB:TOT_040000121; -.
DR eggNOG; ENOG502SCFS; Eukaryota.
DR OrthoDB; 227253at2759; -.
DR Proteomes; UP000003786; Chromosome 4.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:BAM41739.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003786};
KW Transferase {ECO:0000313|EMBL:BAM41739.1}.
FT DOMAIN 259..362
FT /note="UPF0020"
FT /evidence="ECO:0000259|Pfam:PF01170"
FT REGION 390..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 64485 MW; 22EDD0B103EC084B CRC64;
MTVSYFNFKF NVILKCLRGI EHNLFNELQS FGIERNSLIR SKCKIKVLDC DLKHVYFLSH
FSRLASNVYI EVGRIQLSDK KNVFKSCESI QWNSFLSPSN SYLVNCGSLE SNKYINSKLY
ACQLAKDGIK NYFISNLNLE APRVELKNPE VKLELDIDEN CTATVMVDAT GSPLSSRGYR
YKPNIADIDP TMACSILYDL GYTSFSDTAY SIEEYEDHCK EKASADYNDD EDNPGDKLGL
NTAADSIESQ QIEDFKRPRI VDLFSGCGVF LIESALWAAR IPPGYLKTKF ALKKMPIHDD
IAYKSLITYT NGKKARQGSK EWSQLSGSFI GIERDWEKVE ASLKSSEKAG VLELMSFNQA
DYLKDGIKDA RAASGGREWE YMIAQLPQMK EPSCNHSSNG DDSEAIKAVD SLGDGGDSNG
KDEGPKTKLE KEYGKDKSGK KNKLSANRYL KLVKSLARVK KKYFQEGAKG ALMMPSFIDK
VYVEDSFSAK LSAGKTYSKN GINTITYYTG LVGRDHGALD AGARPPGPDD PANVRVGVID
SANNVSIDAV ERIGHEDVVV LNGDFVQRSF LLVSIVVEES
//
