ID J4HWK4_9APHY Unreviewed; 451 AA.
AC J4HWK4;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Histone H2B {ECO:0000256|RuleBase:RU000451};
GN ORFNames=FIBRA_04515 {ECO:0000313|EMBL:CCM02417.1};
OS Fibroporia radiculosa.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Fibroporiaceae; Fibroporia.
OX NCBI_TaxID=599839 {ECO:0000313|EMBL:CCM02417.1, ECO:0000313|Proteomes:UP000006352};
RN [1] {ECO:0000313|EMBL:CCM02417.1, ECO:0000313|Proteomes:UP000006352}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TFFH 294 {ECO:0000313|EMBL:CCM02417.1,
RC ECO:0000313|Proteomes:UP000006352};
RX PubMed=22247176; DOI=10.1128/AEM.06745-11;
RA Tang J.D., Perkins A.D., Sonstegard T.S., Schroeder S.G., Burgess S.C.,
RA Diehl S.V.;
RT "Short-read sequencing for genomic analysis of the brown rot fungus
RT Fibroporia radiculosa.";
RL Appl. Environ. Microbiol. 78:2272-2281(2012).
CC -!- SUBUNIT: The nucleosome is a histone octamer containing two molecules
CC each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and
CC two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of
CC DNA. {ECO:0000256|RuleBase:RU000451}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU000451}.
CC -!- SIMILARITY: Belongs to the histone H2B family.
CC {ECO:0000256|ARBA:ARBA00006846, ECO:0000256|RuleBase:RU000451}.
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DR EMBL; HE797078; CCM02417.1; -; Genomic_DNA.
DR RefSeq; XP_012181700.1; XM_012326310.1.
DR AlphaFoldDB; J4HWK4; -.
DR STRING; 599839.J4HWK4; -.
DR GeneID; 24097328; -.
DR HOGENOM; CLU_606954_0_0_1; -.
DR InParanoid; J4HWK4; -.
DR OrthoDB; 1381287at2759; -.
DR Proteomes; UP000006352; Unassembled WGS sequence.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 2.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR007125; Histone_H2A/H2B/H3.
DR InterPro; IPR000558; Histone_H2B.
DR InterPro; IPR029069; HotDog_dom_sf.
DR PANTHER; PTHR28152; HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR28152:SF1; HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL; 1.
DR Pfam; PF00125; Histone; 1.
DR PRINTS; PR00621; HISTONEH2B.
DR SMART; SM00427; H2B; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
DR PROSITE; PS00357; HISTONE_H2B; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|RuleBase:RU000451};
KW DNA-binding {ECO:0000256|RuleBase:RU000451};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Nucleosome core {ECO:0000256|RuleBase:RU000451};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU000451};
KW Reference proteome {ECO:0000313|Proteomes:UP000006352};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 312..425
FT /note="Histone H2A/H2B/H3"
FT /evidence="ECO:0000259|Pfam:PF00125"
FT REGION 312..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 49677 MW; A6421BA2CD642A31 CRC64;
MPLLTTACRM RVLVPGGLIR SYSTPVSVAN LAALDAWIRH EKILTLTDTL RPEHLSDLYV
TLPTRDGTIA PFQPPTEQTP LGYGHHLVFF HPRNPEHALR SDGTDTDFCP PEPWTRRMCA
GGRIVWRHPL LIGEKAVATA RVSSVEKKGF EKGSPMVFVK QKIEYRKEGS DEVAIEEERS
HVYLASPGNR REARIVKDLP ASPKFCLKYT PSPTTLFRFS ALTFNGHYIH LDKDYAQRSE
GYAERLVHGP LTALMLLDTY ATQSFDIAVK SFEYRAINPL VASSTRGGTL LTLCPLLAPS
LAPISKLMAP KPASTASKAP ASTASKAPAK SETSKAAKKT SAKPAGPEGE KKKRRKARKE
TYSSYIYKVL KQVHPDTGIS NKAMAILNSF VNDIFERIAT EASKLASYSK KSTISSREIQ
TSVRLILPGE LAKHAISEGT KSVTKFSSSQ K
//
