ID   J4I969_9APHY            Unreviewed;       793 AA.
AC   J4I969;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=PX domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=FIBRA_02678 {ECO:0000313|EMBL:CCM00641.1};
OS   Fibroporia radiculosa.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Fibroporiaceae; Fibroporia.
OX   NCBI_TaxID=599839 {ECO:0000313|EMBL:CCM00641.1, ECO:0000313|Proteomes:UP000006352};
RN   [1] {ECO:0000313|EMBL:CCM00641.1, ECO:0000313|Proteomes:UP000006352}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TFFH 294 {ECO:0000313|EMBL:CCM00641.1,
RC   ECO:0000313|Proteomes:UP000006352};
RX   PubMed=22247176; DOI=10.1128/AEM.06745-11;
RA   Tang J.D., Perkins A.D., Sonstegard T.S., Schroeder S.G., Burgess S.C.,
RA   Diehl S.V.;
RT   "Short-read sequencing for genomic analysis of the brown rot fungus
RT   Fibroporia radiculosa.";
RL   Appl. Environ. Microbiol. 78:2272-2281(2012).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; HE796996; CCM00641.1; -; Genomic_DNA.
DR   RefSeq; XP_012179924.1; XM_012324534.1.
DR   AlphaFoldDB; J4I969; -.
DR   STRING; 599839.J4I969; -.
DR   GeneID; 24095552; -.
DR   HOGENOM; CLU_020758_0_0_1; -.
DR   InParanoid; J4I969; -.
DR   OrthoDB; 1891044at2759; -.
DR   Proteomes; UP000006352; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR019497; Sorting_nexin_WASP-bd-dom.
DR   PANTHER; PTHR45827; SORTING NEXIN; 1.
DR   PANTHER; PTHR45827:SF1; SORTING NEXIN; 1.
DR   Pfam; PF10456; BAR_3_WASP_bdg; 1.
DR   Pfam; PF00787; PX; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006352};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          88..161
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          298..436
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          58..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          173..202
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          243..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          328..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          526..546
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..202
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        333..356
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   793 AA;  87624 MW;  A93DE4956EAA533E CRC64;
     MAKQSPVRPL SPVSSNIATF LLPSSSPRSG TLSDTEFDSG LNTSAAWTVS LASTPETLLH
     PVVETNAKSL SDEEPGGDSD EDPDADNEPG RPARALYFFE GKPEFRELAC VEAGDELEVL
     KEDVGDGWSL VKITKSRKEG DEGRQGEVGL LPQTYYTFTA DFALLPGFAL PSAHTRSRTR
     REASGSSITP RGSPSRGSQP LPLVPQFTGE WFPSFRRSLL GGRSLNRFSN FVTSGAEEFV
     LQGSAESDAP PPQSHSRQSS EHGVHGDDSN RQSMLGMASE TERHFVDVGP TWKSKLPAFR
     VLVHSPSKRS SSLTGQYTVY TLTSIFEPQP AHDRAGSEPE SDSETESDTD KDSRPASITV
     QRRFSHFVVL HTALSRRLPG IALPPLPEKQ YAGRFNDEFV EARRGDLERY INRVVRHPVA
     RYAEMLTFFL GCESDVEWKR QLPQYLSLPP KGPSFYAEVY HPAFNLDADE ASETVDKFVS
     HTRAAGKGVQ GLRNIFGKIR EARIEMSKAE RLLSYSFLSL ITSKPLASTS NGGSIEEEEE
     DESRTKGLLN GDGAWCWREN CEGALVRVEA PHDTDEGEDC LRLTKAVQKT SETLQSVADL
     YDSHARKTQL ATHESLKNVA HPATIFAPVI DTHKSTLSRY NEAIREGEED EETAARCETV
     LNTTMAEMDT YHTQKVDDFQ AIAKDHLDGE IVLYEQTDHT PCQRQILTRL RAARQMFDTP
     QYTTLAEGPR QPSMYERELD HPRLAPAPLT QPCPHVFDSA PIRPVSAAIQ EGVGMLLGGV
     APSTRASVFG KLW
//