ID J4KLF3_BEAB2 Unreviewed; 570 AA.
AC J4KLF3;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Peptidase S8/S53, subtilisin/kexin/sedolisin {ECO:0000313|EMBL:EJP62104.1};
GN ORFNames=BBA_08901 {ECO:0000313|EMBL:EJP62104.1};
OS Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus)
OS (Tritirachium shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=655819 {ECO:0000313|EMBL:EJP62104.1, ECO:0000313|Proteomes:UP000002762};
RN [1] {ECO:0000313|EMBL:EJP62104.1, ECO:0000313|Proteomes:UP000002762}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2860 {ECO:0000313|EMBL:EJP62104.1,
RC ECO:0000313|Proteomes:UP000002762};
RX PubMed=22761991; DOI=10.1038/srep00483;
RA Xiao G., Ying S.H., Zheng P., Wang Z.L., Zhang S., Xie X.Q., Shang Y.,
RA St Leger R.J., Zhao G.P., Wang C., Feng M.G.;
RT "Genomic perspectives on the evolution of fungal entomopathogenicity in
RT Beauveria bassiana.";
RL Sci. Rep. 2:483-483(2012).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; JH725191; EJP62104.1; -; Genomic_DNA.
DR RefSeq; XP_008602220.1; XM_008603998.1.
DR AlphaFoldDB; J4KLF3; -.
DR STRING; 655819.J4KLF3; -.
DR GeneID; 19891913; -.
DR HOGENOM; CLU_016268_0_0_1; -.
DR InParanoid; J4KLF3; -.
DR OrthoDB; 2491836at2759; -.
DR Proteomes; UP000002762; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00306; Peptidases_S8_S53; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000002762};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 266..495
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT ACT_SITE 274
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 322
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 477
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 570 AA; 64221 MW; AAF2882B1DB3AF6A CRC64;
MRSLAELIEL SQVERDRTRP VSVKDRYRLC YNLALSAYCL SSAAWRRLRW CKRKTFDANV
FLHHDSTTGI IHDPTEAYLS CPIEAPLPQL EAGPDLKCDL NLLELGKILV EVRFWRKPDV
FSEAHGRSWE EGIRRQLGLL ITDHPDLLDS ESPFVDAIKA CLSYEGKVAA KKKTTREFLT
FFEEHILKPL SILLPDCPGA EEPKEDYLSD VETQREPLTA LPHKREPGPK SARAKEFMSR
MQKFAISYVN PLSVKSRTPL PEDRSRKVRI AVIDSGISSS DSEIRIALRD SDIGLGLRDR
RIAGLRNFCG TSVDDCEDYH GHGTTVAKIL LEAAPQAEIY IAKVTNSSTV SDDELHNVRK
AINWAVQVWD ADIINLSLAM RVESRDIDEA LSHALLPGSK IIFAAAHNNA GHHEGPSWPG
RKLGIIAIHC TDGDGQPLST NASVGREDYF ATLGLDIPIK EQFATTKSQY VYASGVSYAT
PIAAGIAANM LEILRHEASH RVNDVKKWFY NGRYMKVLFK AISQRDHRCC FVQPWTFWHE
IISVSPRYRD VQLRSGDERN IIRVLELLAA
//
