ID J4KP51_BEAB2 Unreviewed; 662 AA.
AC J4KP51;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=glycine--tRNA ligase {ECO:0000256|ARBA:ARBA00012829};
DE EC=6.1.1.14 {ECO:0000256|ARBA:ARBA00012829};
DE AltName: Full=Diadenosine tetraphosphate synthetase {ECO:0000256|ARBA:ARBA00030057};
GN ORFNames=BBA_04137 {ECO:0000313|EMBL:EJP66844.1};
OS Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus)
OS (Tritirachium shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=655819 {ECO:0000313|EMBL:EJP66844.1, ECO:0000313|Proteomes:UP000002762};
RN [1] {ECO:0000313|EMBL:EJP66844.1, ECO:0000313|Proteomes:UP000002762}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2860 {ECO:0000313|EMBL:EJP66844.1,
RC ECO:0000313|Proteomes:UP000002762};
RX PubMed=22761991; DOI=10.1038/srep00483;
RA Xiao G., Ying S.H., Zheng P., Wang Z.L., Zhang S., Xie X.Q., Shang Y.,
RA St Leger R.J., Zhao G.P., Wang C., Feng M.G.;
RT "Genomic perspectives on the evolution of fungal entomopathogenicity in
RT Beauveria bassiana.";
RL Sci. Rep. 2:483-483(2012).
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00008226}.
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DR EMBL; JH725158; EJP66844.1; -; Genomic_DNA.
DR RefSeq; XP_008597456.1; XM_008599234.1.
DR AlphaFoldDB; J4KP51; -.
DR STRING; 655819.J4KP51; -.
DR GeneID; 19887149; -.
DR HOGENOM; CLU_015515_1_0_1; -.
DR InParanoid; J4KP51; -.
DR OrthoDB; 546660at2759; -.
DR Proteomes; UP000002762; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00774; GlyRS-like_core; 1.
DR Gene3D; 3.30.40.230; -; 1.
DR Gene3D; 3.30.720.200; -; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR027031; Gly-tRNA_synthase/POLG2.
DR InterPro; IPR033731; GlyRS-like_core.
DR InterPro; IPR002315; tRNA-synt_gly.
DR NCBIfam; TIGR00389; glyS_dimeric; 1.
DR PANTHER; PTHR10745:SF0; GLYCINE--TRNA LIGASE; 1.
DR PANTHER; PTHR10745; GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR PRINTS; PR01043; TRNASYNTHGLY.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000313|EMBL:EJP66844.1}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000002762}.
FT DOMAIN 201..548
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT REGION 123..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 662 AA; 74068 MW; 48617C307ECAFBFF CRC64;
MTSQATTLKG QPLDKPVLDA MLRRRMFYTP SFEIYGGVGG LYDYGPPGCA LQANIVDIWR
KHFVLEEDML EVDCTALTPH DILKTSGHVD KFSDFMCKDP KNGEIMRADH FVEAVLEARL
KGDKEARGEK VEEKDDPKKK KKKTKTEAVK LDDAVVQEYE EVLAKIDNYG GAELGELIKK
YDLKNPATGL LPSEPVAFNL MFQTSIGPSS NLPGFLRPET AQGQFLNFAK LLEFNQSQMP
FASASIGKSY RNEISPRAGL LRVREFLMAE IEHYVDPEGG KKHGRFHEVE DLELVLLDKG
TQLSGKTTTK TMTIGQAVKD GVVDNETLGY FLARIHLFLQ KIGVDMSKLR FRQHMANEMA
HYACDCWDAE LLTTTGWVEC VGCADRSAYD LTVHAKKTGA PLLVRERLEQ PRVIEEWQLD
IDKKKFGPLF KKDAKAVETA LEATTQEQRE AFSKQLAEGG KISLDVPGVG DGKAEVTSDS
IKIEFRKRVE NTREFTPNVI EPSFGIGRIL YSLIEHNFWT RGSDGSDEAR GVLSFPPPVA
PTKVLLVPLS SNAQFKPEVR KLSQRLRAMG ISSRVDDSSA SIGKRYSRND ELGTPLGITV
DFQTLQDQTI TLRDRDSTTQ VRADEARILE AIKSLVDGSK NWAKIQEELP KFEGQEVEVA
QR
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