ID   J4KPE1_BEAB2            Unreviewed;      1144 AA.
AC   J4KPE1;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Piwi domain-containing protein {ECO:0000313|EMBL:EJP67294.1};
GN   ORFNames=BBA_03868 {ECO:0000313|EMBL:EJP67294.1};
OS   Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus)
OS   (Tritirachium shiotae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX   NCBI_TaxID=655819 {ECO:0000313|EMBL:EJP67294.1, ECO:0000313|Proteomes:UP000002762};
RN   [1] {ECO:0000313|EMBL:EJP67294.1, ECO:0000313|Proteomes:UP000002762}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ARSEF 2860 {ECO:0000313|EMBL:EJP67294.1,
RC   ECO:0000313|Proteomes:UP000002762};
RX   PubMed=22761991; DOI=10.1038/srep00483;
RA   Xiao G., Ying S.H., Zheng P., Wang Z.L., Zhang S., Xie X.Q., Shang Y.,
RA   St Leger R.J., Zhao G.P., Wang C., Feng M.G.;
RT   "Genomic perspectives on the evolution of fungal entomopathogenicity in
RT   Beauveria bassiana.";
RL   Sci. Rep. 2:483-483(2012).
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DR   EMBL; JH725157; EJP67294.1; -; Genomic_DNA.
DR   RefSeq; XP_008597187.1; XM_008598965.1.
DR   AlphaFoldDB; J4KPE1; -.
DR   STRING; 655819.J4KPE1; -.
DR   GeneID; 19886880; -.
DR   HOGENOM; CLU_004544_4_1_1; -.
DR   InParanoid; J4KPE1; -.
DR   OrthoDB; 3060088at2759; -.
DR   Proteomes; UP000002762; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd04657; Piwi_ago-like; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 2.170.260.10; paz domain; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR014811; ArgoL1.
DR   InterPro; IPR032472; ArgoL2.
DR   InterPro; IPR036085; PAZ_dom_sf.
DR   InterPro; IPR003165; Piwi.
DR   InterPro; IPR045246; Piwi_ago-like.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR22891; EUKARYOTIC TRANSLATION INITIATION FACTOR 2C; 1.
DR   PANTHER; PTHR22891:SF188; INTERFERENCE AND GENE SILENCING PROTEIN (QDE2), PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05280)-RELATED; 1.
DR   Pfam; PF08699; ArgoL1; 1.
DR   Pfam; PF16488; ArgoL2; 1.
DR   Pfam; PF02171; Piwi; 1.
DR   SMART; SM01163; DUF1785; 1.
DR   SMART; SM00950; Piwi; 1.
DR   SUPFAM; SSF101690; PAZ domain; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50822; PIWI; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002762}.
FT   DOMAIN          791..1107
FT                   /note="Piwi"
FT                   /evidence="ECO:0000259|PROSITE:PS50822"
FT   REGION          1..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          267..313
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1..17
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1144 AA;  126263 MW;  5C85ACDBFF6C2C02 CRC64;
     MSDSRGGRGR RNHRGGRGGG DVGGGGGDDG RRNFSQGDGH RGGGYRGGGE RGGGYRGGGE
     RGGGYRGGGD RGGGERSNGQ RGGGQRGGGY RGNREGGNDT PYQGSFSAPN RERGGRGGGR
     PYQGGRGGGR GGGGNDDRRP ECFSAPDQSP VPDSEVTKSE DMLVKPQGDA LVKRIAAGNG
     KSSREYKFDE PLPARPAFGT VGNKVVVWAN FFEVKAQPVM LFRHGLKITK VNPQDEKNKS
     FSQTEVRGRK LHFVIAKLLE QIRAAPAQAL EEAETRLERA KQAEKAANGR KAAAEAKEEV
     KNATEAKLDA QTALNSGKLV VSEFKSQIIS LKELHLDKGP IRVVLYEDAI EDGAPRREEL
     FDVQLTDAVP VKLSEVLEYV THMKVAENDL VFPRHPEVVD VLNMVLSFRP RSSTDVSAVG
     SSRLYPFGDG PSADIAKLLW DQRPLVAARG FFQSARLASG RILLNTQVTH GVFKFGGKAI
     ELFKVMGLGP YGAGKIDMQR YDTIAALKIF SKYINKVRAV VTFETPSGRK VERFKTIQGL
     VIQSAMKKQK SGPGEHPDRF AKGWEVCGPE HIEFWNADDK KYVSVRQHYK TKYGKQLGNY
     PVFRFGQGDK ISYFPAENVM IQHGQSAKLK LDGGETKLMM QSACRPPISN AKTIVEQGRQ
     FLGHDDPLLE QFGVSVSKQL LAVHARVMQP PMIQYLTAGK TKKYVEPAKA SWNMIKCCVA
     KPGRSIQNWA YVQIDCHWIT PEQVDAMVFA WQNMGIDIAN EPCFSKKLDA PDSIQSMDAI
     FKQSKSKDVQ LIIFILRERD SGPLYNRIKT LGDCVYGIHT SCMVSQHLTK PQIGNFANLG
     IKVNLKFGGV NHKLRDELDI LKKGNTMFVG YDVTHPTNMD IPKGATGPPS LVGLVSSIDS
     ELGQWPSVTW EQASKQEMLG AVLEQHFASR IDLWQKNYKN KGKPLKNIVI YRDGVSESQF
     ATVLTDELPL IRKACKKKFG DKPPKLTIIV SVKRHQTRFY PAQEQHMTRS GNIENGTVVD
     RGVTQARYWD FYLTAHDVFK GTARPAHYTV LLDEVFRPEY GLQAANELQK LTHELCYLFG
     RATKAVSICP PAYYADIVCE RARAHRPEYA VPDDAASERS GSSMHGPAVA REIHPNLRDT
     MYYI
//