ID J4KQV9_BEAB2 Unreviewed; 1018 AA.
AC J4KQV9;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Transport protein sec24 {ECO:0000313|EMBL:EJP69884.1};
GN ORFNames=BBA_00753 {ECO:0000313|EMBL:EJP69884.1};
OS Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus)
OS (Tritirachium shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=655819 {ECO:0000313|EMBL:EJP69884.1, ECO:0000313|Proteomes:UP000002762};
RN [1] {ECO:0000313|EMBL:EJP69884.1, ECO:0000313|Proteomes:UP000002762}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2860 {ECO:0000313|EMBL:EJP69884.1,
RC ECO:0000313|Proteomes:UP000002762};
RX PubMed=22761991; DOI=10.1038/srep00483;
RA Xiao G., Ying S.H., Zheng P., Wang Z.L., Zhang S., Xie X.Q., Shang Y.,
RA St Leger R.J., Zhao G.P., Wang C., Feng M.G.;
RT "Genomic perspectives on the evolution of fungal entomopathogenicity in
RT Beauveria bassiana.";
RL Sci. Rep. 2:483-483(2012).
CC -!- FUNCTION: Component of the coat protein complex II (COPII) which
CC promotes the formation of transport vesicles from the endoplasmic
CC reticulum (ER). The coat has two main functions, the physical
CC deformation of the endoplasmic reticulum membrane into vesicles and the
CC selection of cargo molecules. {ECO:0000256|ARBA:ARBA00025471}.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004255}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004255}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004255}.
CC -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC {ECO:0000256|ARBA:ARBA00008334}.
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DR EMBL; JH725151; EJP69884.1; -; Genomic_DNA.
DR RefSeq; XP_008594072.1; XM_008595850.1.
DR AlphaFoldDB; J4KQV9; -.
DR STRING; 655819.J4KQV9; -.
DR GeneID; 19883765; -.
DR HOGENOM; CLU_004589_1_0_1; -.
DR InParanoid; J4KQV9; -.
DR OrthoDB; 977017at2759; -.
DR Proteomes; UP000002762; Unassembled WGS sequence.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR006895; Znf_Sec23_Sec24.
DR InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR PANTHER; PTHR13803:SF4; SECRETORY 24CD, ISOFORM C; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR Pfam; PF04810; zf-Sec23_Sec24; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR SUPFAM; SSF82919; Zn-finger domain of Sec23/24; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000002762};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 293..331
FT /note="Zinc finger Sec23/Sec24-type"
FT /evidence="ECO:0000259|Pfam:PF04810"
FT DOMAIN 371..614
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 621..705
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 727..828
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT DOMAIN 857..902
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 98..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 153..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1018 AA; 110478 MW; 640E743BCB39994A CRC64;
MADYNQFHAL GHGEQYDPND PNKTTAPAAQ QFMPPVAPNP YQQQQQYGAP PYHGGQAPPM
SGLPSPGFQG GAPPPQQDAL AAQMGGMSLG GDVQGTVRRK KKDRHAYHTV EPTGSSQAFN
GMPTAGVGAS QFLNNSGSPS IPAFGNQFDS QGAPHTQYGA PAASPLGGPI NPITGSTSGD
AAASVPASGQ GKVSADDLPS VPAARDAIQQ YFLNNIYPTF EKHVPPPASV SFVAHDQGNS
SPKYARLTMN NVPATPDGLQ ATGIPLGLLL QPLAPLQAGE AEIPVLDFGE AGPPRCRRCR
AYINPLMMFR SGGNKFVCNL CTYPNDTPPE YFCATSPQGV RVDRDQRPEL HRGTVEFVVP
KEYWTRPPVG LRFLFLIDVT QESFNKGFLE SFCDGIQAAL YGGEIGEDGE PKRRIPEGAK
VGFVTYDQDI HFYNINPGLD QAHMLIMPDL EDPFLPLGEG LFVDPYECKS TITSLLNRLP
EMFSTVKNPE PAMLAALSSG LAALEATGGK VICSCAALPT WGPGRLFLRD DGSHPGGESD
KKLYTTEHPG WKKVSEKMAA SGVGVDFFLA APSGGYLDIG TIGHVAATTG GETFYYPNFI
APRDSPRLST EIAHAVTRET GFQALMKVRC SNGLQIAAYH GNFVQHTFGA DLEIGVIDAD
KALGVSFSYD GKLDAKLDAH FQSALLYTTA SGQRRVRCSN IIASVSDTSK EAGVREQGIR
ACMKFVDQDA VIALLAKEAS TKLSTTSSSL KDTRNWLTER TIDIMSCYRK HSAQQHPPGQ
LVMPERLKEF CMYMLGLLKC RAYKGGIENT DRRVYEMRLV RSMGALELSL YLYPRMIPLH
NLNPEDGFAD AETGHLKMPP CVRASFSRVE PGGVYLVDNG QQCLIWFHAQ TSPNLISDLF
GEGKDTLKSL DAYTSSLPVL DTHLNAQARN IIEFLKTQRG SKGMNIQLAR QGIDGAEFEF
ARLLVEDRNN EAQSYVDWLV HVHKGVQLEL SGQRKRETEA DNAANSLTNF AGLRPSYW
//
