ID   J4KRA9_BEAB2            Unreviewed;       773 AA.
AC   J4KRA9;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=YSIRK family gram-positive signal peptide {ECO:0000313|EMBL:EJP70634.1};
GN   ORFNames=BBA_00264 {ECO:0000313|EMBL:EJP70634.1};
OS   Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus)
OS   (Tritirachium shiotae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX   NCBI_TaxID=655819 {ECO:0000313|EMBL:EJP70634.1, ECO:0000313|Proteomes:UP000002762};
RN   [1] {ECO:0000313|EMBL:EJP70634.1, ECO:0000313|Proteomes:UP000002762}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ARSEF 2860 {ECO:0000313|EMBL:EJP70634.1,
RC   ECO:0000313|Proteomes:UP000002762};
RX   PubMed=22761991; DOI=10.1038/srep00483;
RA   Xiao G., Ying S.H., Zheng P., Wang Z.L., Zhang S., Xie X.Q., Shang Y.,
RA   St Leger R.J., Zhao G.P., Wang C., Feng M.G.;
RT   "Genomic perspectives on the evolution of fungal entomopathogenicity in
RT   Beauveria bassiana.";
RL   Sci. Rep. 2:483-483(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TMCO4 family.
CC       {ECO:0000256|ARBA:ARBA00009824}.
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DR   EMBL; JH725150; EJP70634.1; -; Genomic_DNA.
DR   RefSeq; XP_008593583.1; XM_008595361.1.
DR   AlphaFoldDB; J4KRA9; -.
DR   GeneID; 19883276; -.
DR   HOGENOM; CLU_007407_3_0_1; -.
DR   InParanoid; J4KRA9; -.
DR   OrthoDB; 8526at2759; -.
DR   Proteomes; UP000002762; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR007941; DUF726.
DR   PANTHER; PTHR17920:SF3; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4; 1.
DR   PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR   Pfam; PF05277; DUF726; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002762};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        314..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        355..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          41..136
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          182..204
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          717..773
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..89
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        758..773
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   773 AA;  83620 MW;  7DA87578E7BC1001 CRC64;
     MAPFCSDPRQ IVIALEPRRR IELLKLVDDI IFSMTAQLQS KPEELGSVSV ESSIHGGSGT
     PQNEKTFDSP SPTGDANKTE TSSESITLFD AEDTEFGNAA PANGSKKKFS PSNPFKNVKV
     GVPWKNNPSA PSKTTKRAEE VQSAARQYME EWEHEFVPKL EEIVRVKDND KITAERKIRR
     QAVQMNEENE RAESKRRAGS DEARDEEAAF AVMQTLYPPI PTSLTELSVH DRREAISCVL
     LLLLSTGKYS AHSRALMLTL TSSLDIPHAF LNNEEAAIAE SLIEQSTADK GKKEAMSADA
     EAAKRQQDNK FGRYWKVGLA SVAGATLIGV TGGLAAPLVA GAVGSILGGV GLGGVASFLG
     IFWMNGALVG ALFGAYGAKM TGSMMDKYAK EVEDFKFIPL HEPPEATDRT PSAKGRRLRV
     TLGINGWLNS EDDITKPWEA LPADSEVFAL RYEMQTLLAL GTALGDLVQS FAWKAVKAEI
     IKRTVLATLW AALWPIQVFA VASNVDNPFN HASNRSKKAG RLLADALINR VQGERPVTLI
     GYSLGAAAIH ACLQELAARR AFGLIDTVVL MGAPAPSDPA HWRTLRAVVS GAIFNAYSEN
     DMILGYVHRM HSLSLGVAGL QPIRGVAGVE NLDLSDRVSG HLRYPHLIGG ILRRCGFAGV
     RVDEPIEKDD VILLKDEYAA GHAVNVDGTT IAPAGDEKAG DAKGDVEKVA SQTERLQLGI
     KEQEVLPPPP PRPSHKAGEE EPPKMRRKPV PAPSPSKSQD DDDAKPISMM DLE
//