ID J4VTB7_9PORP Unreviewed; 249 AA.
AC J4VTB7;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EJU17846.1};
DE EC=4.2.1.75 {ECO:0000313|EMBL:EJU17846.1};
GN Name=hemD {ECO:0000313|EMBL:EJU17846.1};
GN ORFNames=HMPREF1323_0920 {ECO:0000313|EMBL:EJU17846.1};
OS Porphyromonas sp. oral taxon 279 str. F0450.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Porphyromonas.
OX NCBI_TaxID=1125723 {ECO:0000313|EMBL:EJU17846.1, ECO:0000313|Proteomes:UP000004156};
RN [1] {ECO:0000313|EMBL:EJU17846.1, ECO:0000313|Proteomes:UP000004156}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0450 {ECO:0000313|EMBL:EJU17846.1,
RC ECO:0000313|Proteomes:UP000004156};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJU17846.1}.
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DR EMBL; ALKJ01000010; EJU17846.1; -; Genomic_DNA.
DR RefSeq; WP_009432385.1; NZ_ALKJ01000010.1.
DR AlphaFoldDB; J4VTB7; -.
DR PATRIC; fig|1125723.3.peg.250; -.
DR Proteomes; UP000004156; Unassembled WGS sequence.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0033014; P:tetrapyrrole biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR Pfam; PF02602; HEM4; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:EJU17846.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004156}.
FT DOMAIN 25..229
FT /note="Tetrapyrrole biosynthesis uroporphyrinogen III
FT synthase"
FT /evidence="ECO:0000259|Pfam:PF02602"
SQ SEQUENCE 249 AA; 28372 MW; 6CC54A815C2E9D88 CRC64;
MSIKTILISQ PRPESGKSPY YDIAARYGAE ATFRAFIEVE SVTPREFRNQ KVNILDHTAI
VFTSRKAMEH FFQLSEELRV TIPEDMKYFC INEQVANYLQ KFIVYRKRKV FYPEAGGQAE
LVAIMQKHSK ELYFLPMAED HKNDLIDLLT SKKLQFTKAI MYRTVSKKFT AAEKKEKYDM
IIFFSPAGVA SLLANHSDYK QGKVLIGGFG PATCQAIEQA GLRLDLSAPI DGAPSMAMAL
EQYLKEKNK
//
