ID J4VWJ3_BEAB2 Unreviewed; 871 AA.
AC J4VWJ3;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=HEAT repeat containing protein {ECO:0000313|EMBL:EJP62760.1};
GN ORFNames=BBA_08305 {ECO:0000313|EMBL:EJP62760.1};
OS Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus)
OS (Tritirachium shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=655819 {ECO:0000313|EMBL:EJP62760.1, ECO:0000313|Proteomes:UP000002762};
RN [1] {ECO:0000313|EMBL:EJP62760.1, ECO:0000313|Proteomes:UP000002762}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2860 {ECO:0000313|EMBL:EJP62760.1,
RC ECO:0000313|Proteomes:UP000002762};
RX PubMed=22761991; DOI=10.1038/srep00483;
RA Xiao G., Ying S.H., Zheng P., Wang Z.L., Zhang S., Xie X.Q., Shang Y.,
RA St Leger R.J., Zhao G.P., Wang C., Feng M.G.;
RT "Genomic perspectives on the evolution of fungal entomopathogenicity in
RT Beauveria bassiana.";
RL Sci. Rep. 2:483-483(2012).
CC -!- SIMILARITY: Belongs to the TOG/XMAP215 family.
CC {ECO:0000256|ARBA:ARBA00025722}.
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DR EMBL; JH725182; EJP62760.1; -; Genomic_DNA.
DR RefSeq; XP_008601624.1; XM_008603402.1.
DR AlphaFoldDB; J4VWJ3; -.
DR STRING; 655819.J4VWJ3; -.
DR GeneID; 19891317; -.
DR HOGENOM; CLU_008401_0_0_1; -.
DR InParanoid; J4VWJ3; -.
DR OrthoDB; 5477703at2759; -.
DR Proteomes; UP000002762; Unassembled WGS sequence.
DR GO; GO:0043232; C:intracellular non-membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0099080; C:supramolecular complex; IEA:UniProt.
DR GO; GO:0061863; F:microtubule plus end polymerase; IEA:InterPro.
DR GO; GO:0051010; F:microtubule plus-end binding; IEA:InterPro.
DR GO; GO:0030951; P:establishment or maintenance of microtubule cytoskeleton polarity; IEA:InterPro.
DR GO; GO:0046785; P:microtubule polymerization; IEA:InterPro.
DR GO; GO:0007051; P:spindle organization; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR048492; Stu2_CTS.
DR InterPro; IPR034085; TOG.
DR InterPro; IPR045110; XMAP215.
DR InterPro; IPR048491; XMAP215_CLASP_TOG.
DR PANTHER; PTHR12609:SF0; CYTOSKELETON-ASSOCIATED PROTEIN 5; 1.
DR PANTHER; PTHR12609; MICROTUBULE ASSOCIATED PROTEIN XMAP215; 1.
DR Pfam; PF21042; Stu2_CTS; 1.
DR Pfam; PF21041; XMAP215_CLASP_TOG; 2.
DR SMART; SM01349; TOG; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002762}.
FT DOMAIN 1..233
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 274..506
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REGION 225..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 769..852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..241
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..266
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 577..594
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 871 AA; 94309 MW; B438BCB5EB69085A CRC64;
MAEEEDYSSI PLPDRFTHKL WKVRKGAYEE AAKQFALTPD ESDPFFRPFL SDVGLWKSAV
LDANVVSQQE GVIALCAFLK YAGRDAGLRT RNHTIGPIVE KCLSSSRAAT KQNGIEALLL
YVELDVAGPV VEDVLPGLAH RTPKNVAATL NALTQIVHNY GCKIVDPKPI LKALPKAFGA
ADKNVRAEAT SLTVELYRWL REAMKPLFWG ELKPTQHTDL EAQFEKVKAE PPPKQERLLR
SQQEVVEAAP EDDGDGYDEG GDEPEGADEL DAFALAEPVD VSKKISPNFT ELLASSKWKD
RKEAVDGLYE ALNVPRIKET DFGEVNRGLA KCMKDANVLV VTQAALCIEL LAKGLRQSFA
KYRAIVMQPI MERLKEKKQT VSDALSAALD AVFASTTFSD CMEDITTALG NKNPQVKEGT
MKFLIRCLRT TRDVPSKPEI AAVCESGKKL LAESTPGLRD GGAEILGTVM KIIGERAMTP
LIEGLDDIRK TKVKEFYASA EVKAKEKPKA PPAPKAAPKK AVAGKRPVAK KAAPVMPATE
PPAKPGSKLG MPKSSGLGGL KAPQKRTLAA PGTASPRRPA AGPPIMPSDD EPVAPPAQPR
IGASRGLAGR SLAKSAAAPA MPPPDSPPRV SGFSAVERAE LEELRAANDR LTRQVDDMRQ
ERSKFLSEIQ ELKNQNAGLI EDHTRDVLSI KAKETQLVRA RSDAEATEGV NDRLRRELER
LKRALNKAET IGGGSGVVSP AITSPTRDDV GIFHDAGLAS GGYSRASFAS TMTEEKENSE
MVYPRNKISP ELRYGSGASS GRGSPARGYR TANPPREESV DSMGPPRRER PVSSLPQPSG
GGESWRRAAE VTSQLKARIE QMKAKQGFAR P
//
