ID J4XNK6_9FIRM Unreviewed; 365 AA.
AC J4XNK6;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Transporter, small conductance mechanosensitive ion channel MscS family protein {ECO:0000313|EMBL:EJO22416.1};
GN ORFNames=HMPREF1148_0304 {ECO:0000313|EMBL:EJO22416.1};
OS Selenomonas sp. FOBRC6.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC Selenomonas.
OX NCBI_TaxID=936572 {ECO:0000313|EMBL:EJO22416.1, ECO:0000313|Proteomes:UP000006984};
RN [1] {ECO:0000313|EMBL:EJO22416.1, ECO:0000313|Proteomes:UP000006984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FOBRC6 {ECO:0000313|EMBL:EJO22416.1,
RC ECO:0000313|Proteomes:UP000006984};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJO22416.1}.
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DR EMBL; ALKG01000101; EJO22416.1; -; Genomic_DNA.
DR RefSeq; WP_009656405.1; NZ_ALKG01000101.1.
DR AlphaFoldDB; J4XNK6; -.
DR STRING; 936572.HMPREF1148_0304; -.
DR PATRIC; fig|936572.3.peg.1404; -.
DR eggNOG; COG3264; Bacteria.
DR Proteomes; UP000006984; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30566:SF25; INNER MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 139..175
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 177..244
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 253..338
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 365 AA; 40225 MW; 19D39973E59BD03E CRC64;
MTIFSHTIDF NTLIELLIVP VGIVLAALTV GIITDRLIRR YIDHHLAVEE STWKYVLIRS
MQGVPIFFSF IIGLYWAIDA VEISPTLTKL LSYILFTSNV FSITRVLART VDGVVTMYFE
RSGRNLPKTT LLNSILIGVI YAMGLLVILQ YYGISIAPIL TAAGVGGMAV ALALQEMLAN
IFSGLHLILS KQLRIGDYIK LGSGEEGRVT DITWRFTTII PLGASNTIVI PNKTIAGANI
TNYSLPTLNI NVIVPVGVAY DSDLAMVERV TIETAKEVLA RVDNNLTANP LVLYTDFGAS
SINFNVILPS SMFDHQGIIK HEFIKALTDR YRAEGIDIPY PIQTIIQEKA DAEENNPQDA
AHVEK
//
