ID   J5GIX1_9FIRM            Unreviewed;       334 AA.
AC   J5GIX1;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Methyltransferase domain protein {ECO:0000313|EMBL:EJP18818.1};
GN   ORFNames=HMPREF1142_1763 {ECO:0000313|EMBL:EJP18818.1};
OS   Peptostreptococcaceae bacterium AS15.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae.
OX   NCBI_TaxID=936556 {ECO:0000313|EMBL:EJP18818.1, ECO:0000313|Proteomes:UP000006605};
RN   [1] {ECO:0000313|EMBL:EJP18818.1, ECO:0000313|Proteomes:UP000006605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AS15 {ECO:0000313|EMBL:EJP18818.1,
RC   ECO:0000313|Proteomes:UP000006605};
RA   Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA   Nelson K.E.;
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJP18818.1}.
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DR   EMBL; ALJM01000050; EJP18818.1; -; Genomic_DNA.
DR   AlphaFoldDB; J5GIX1; -.
DR   PATRIC; fig|936556.4.peg.2191; -.
DR   OrthoDB; 1682723at2; -.
DR   Proteomes; UP000006605; Unassembled WGS sequence.
DR   GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR031725; ASMT_dimerisation.
DR   InterPro; IPR001077; O_MeTrfase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF16864; Dimerisation2; 1.
DR   Pfam; PF00891; Methyltransf_2; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:EJP18818.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006605};
KW   Transferase {ECO:0000313|EMBL:EJP18818.1}.
FT   DOMAIN          22..91
FT                   /note="Acetylserotonin O-methyltransferase dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF16864"
FT   DOMAIN          145..278
FT                   /note="O-methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00891"
SQ   SEQUENCE   334 AA;  37045 MW;  5B8B8FAF1432552F CRC64;
     MINKTNIYEQ LTTLPYLSAY QQLIQGAIEL DVFSKLKNPI TAKELSEKMN WDESNTFNLL
     KALYSLGYLK RNGDAFCNMP ETAKYLVKGK PTYMGSVLEF FCNNQGMSLG NVVQQVKEGP
     KPMEHLQKSM DFASYGKTMR DAQSGIRQYE LLEILKSLPE YKSIHKMLDL GCGAGCLGIA
     VIQDVGNCTG VFFDRPEMQP LIEETIKLSN MQESISVKTG DFIKDDIGGE YDLIICSSIM
     LFAIAYGTDF FAKLKKALNP GGVVVCINEG IEPDYSGPWD MILGYMSFNL QGMPIGVIKG
     QVADAAKAGG FYSVENRSVL LSTGMHDINI LRNK
//