ID   J5H1K1_9FIRM            Unreviewed;       238 AA.
AC   J5H1K1;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=CRISPR-associated endoribonuclease Cas6 {ECO:0000313|EMBL:EJP23243.1};
DE            EC=3.1.-.- {ECO:0000313|EMBL:EJP23243.1};
GN   Name=cas6_2 {ECO:0000313|EMBL:EJP23243.1};
GN   ORFNames=HMPREF1142_1860 {ECO:0000313|EMBL:EJP23243.1};
OS   Peptostreptococcaceae bacterium AS15.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae.
OX   NCBI_TaxID=936556 {ECO:0000313|EMBL:EJP23243.1, ECO:0000313|Proteomes:UP000006605};
RN   [1] {ECO:0000313|EMBL:EJP23243.1, ECO:0000313|Proteomes:UP000006605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AS15 {ECO:0000313|EMBL:EJP23243.1,
RC   ECO:0000313|Proteomes:UP000006605};
RA   Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA   Nelson K.E.;
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJP23243.1}.
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DR   EMBL; ALJM01000028; EJP23243.1; -; Genomic_DNA.
DR   AlphaFoldDB; J5H1K1; -.
DR   PATRIC; fig|936556.4.peg.923; -.
DR   OrthoDB; 45555at2; -.
DR   Proteomes; UP000006605; Unassembled WGS sequence.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.1890; -; 1.
DR   Gene3D; 3.30.70.1900; -; 1.
DR   InterPro; IPR049435; Cas_Cas6_C.
DR   InterPro; IPR010156; CRISPR-assoc_prot_Cas6.
DR   InterPro; IPR045747; CRISPR-assoc_prot_Cas6_N_sf.
DR   NCBIfam; TIGR01877; cas_cas6; 1.
DR   PANTHER; PTHR36984; CRISPR-ASSOCIATED ENDORIBONUCLEASE CAS6 1; 1.
DR   PANTHER; PTHR36984:SF3; CRISPR-ASSOCIATED PROTEIN CAS6; 1.
DR   Pfam; PF01881; Cas_Cas6_C; 1.
PE   4: Predicted;
KW   Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW   Hydrolase {ECO:0000313|EMBL:EJP23243.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006605}.
FT   DOMAIN          120..235
FT                   /note="CRISPR associated protein Cas6 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01881"
SQ   SEQUENCE   238 AA;  27463 MW;  11A70366F2BBD0C5 CRC64;
     MKYLVRFELK EPNIRVNYRE IFISFFKKSI SSYMDGYFFD DLYNAGTMKK SLVWSVNFQK
     PIFKKDKMEL AGKDVNMTLK IGDSQTALIY SSSMLLMKDK AFPIGDGNEL RLRSIKIINE
     NDIVGDYAVF KIFSPICLKQ HHSENNKDKY LTSEDAEFGL ELGRKLKEDL PYMDEEIDNL
     RYDFSKLKKV IVPIYKVKIP ATIGTFEISG DNKILNHILK NGIGSKRNSG FGLVEQAF
//