ID J5J741_BEAB2 Unreviewed; 484 AA.
AC J5J741;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Zinc-binding dehydrogenase {ECO:0000313|EMBL:EJP62248.1};
GN ORFNames=BBA_08790 {ECO:0000313|EMBL:EJP62248.1};
OS Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus)
OS (Tritirachium shiotae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=655819 {ECO:0000313|EMBL:EJP62248.1, ECO:0000313|Proteomes:UP000002762};
RN [1] {ECO:0000313|EMBL:EJP62248.1, ECO:0000313|Proteomes:UP000002762}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2860 {ECO:0000313|EMBL:EJP62248.1,
RC ECO:0000313|Proteomes:UP000002762};
RX PubMed=22761991; DOI=10.1038/srep00483;
RA Xiao G., Ying S.H., Zheng P., Wang Z.L., Zhang S., Xie X.Q., Shang Y.,
RA St Leger R.J., Zhao G.P., Wang C., Feng M.G.;
RT "Genomic perspectives on the evolution of fungal entomopathogenicity in
RT Beauveria bassiana.";
RL Sci. Rep. 2:483-483(2012).
CC -!- PATHWAY: Secondary metabolite biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005179}.
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DR EMBL; JH725189; EJP62248.1; -; Genomic_DNA.
DR RefSeq; XP_008602109.1; XM_008603887.1.
DR AlphaFoldDB; J5J741; -.
DR STRING; 655819.J5J741; -.
DR GeneID; 19891802; -.
DR HOGENOM; CLU_026673_3_3_1; -.
DR InParanoid; J5J741; -.
DR OrthoDB; 909506at2759; -.
DR Proteomes; UP000002762; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd08267; MDR1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR PANTHER; PTHR11695:SF649; PEPTIDASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002762}.
FT DOMAIN 10..328
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 484 AA; 51376 MW; 37C07E10D2813E7D CRC64;
MKAWQVASPG SIEEKLKLNT NAARPTSEDL KGQDILVKVS SAALNPADYK VMEIGLLVKV
ALSFPKVPGM DLSGEVVAVG PAVTDIIVGD HVLGRLDPFK STGALSEHVV LERDGYAKIA
RDADLDHAAG LGTAALTAYQ SIQPHVKAGD KVFINGGSGG TGTFGIQIAK LLGCHVTATC
STGKIALCKE LGADDVVDYK TTDVLGALQA AGPVYSLFVD NVGAVGDFYA KSSSFLLPTA
PFVAVGGGSV GHAANVVSAM LWPSFLGGGK NRFISYFTKN KHDDLNQLAQ WYSKGSLKSV
VDSTYEFGDA PAAFSHLKKG SSAGKVIVHI AIALHAGFCQ FSSLLLVYHL SARKKEQIQA
AQKLIRPKAN ERAPLTIEVG RHGQRTRDLA VEARNSKTHR QSSLSSYNSA CIRDLCCFDK
LQRHVDQHEA ARLDEICPLN TPCSKHLMNI GAIQAGATPK TSAAHPLSAN SHIDHLLDKL
PQLN
//
