ID J5PMU9_SACK1 Unreviewed; 836 AA.
AC J5PMU9;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=HSF1-like protein {ECO:0000313|EMBL:EJT43128.1};
GN Name=YGL073W {ECO:0000313|EMBL:EJT43128.1};
GN Synonyms=SKDI07G1840 {ECO:0000313|EMBL:CAI4061803.1};
GN ORFNames=SKDI_07G1840 {ECO:0000313|EMBL:CAI4061803.1}, SKUD_205711
GN {ECO:0000313|EMBL:EJT43128.1};
OS Saccharomyces kudriavzevii (strain ATCC MYA-4449 / AS 2.2408 / CBS 8840 /
OS NBRC 1802 / NCYC 2889) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=226230 {ECO:0000313|EMBL:EJT43128.1, ECO:0000313|Proteomes:UP000002753};
RN [1] {ECO:0000313|EMBL:EJT43128.1, ECO:0000313|Proteomes:UP000002753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4449 / AS 2.2408 / CBS 8840 / NBRC 1802 / NCYC 2889
RC {ECO:0000313|Proteomes:UP000002753}, and IFO 1802
RC {ECO:0000313|EMBL:EJT43128.1};
RX PubMed=12775844; DOI=10.1126/science.1084337;
RA Cliften P.F., Sudarsanam P., Desikan A., Fulton L., Fulton B., Majors J.,
RA Waterston R., Cohen B.A., Johnston M.;
RT "Finding functional features in Saccharomyces genomes by phylogenetic
RT footprinting.";
RL Science 301:71-76(2003).
RN [2] {ECO:0000313|EMBL:EJT43128.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IFO 1802 {ECO:0000313|EMBL:EJT43128.1};
RA Cliften P.F., Johnston M.;
RL Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000002753}
RP GENOME REANNOTATION.
RC STRAIN=ATCC MYA-4449 / AS 2.2408 / CBS 8840 / NBRC 1802 / NCYC 2889
RC {ECO:0000313|Proteomes:UP000002753};
RX PubMed=22384314; DOI=10.1534/g3.111.000273;
RA Scannell D.R., Zill O.A., Rokas A., Payen C., Dunham M.J., Eisen M.B.,
RA Rine J., Johnston M., Hittinger C.T.;
RT "The awesome power of yeast evolutionary genetics: New genome sequences and
RT strain resources for the Saccharomyces sensu stricto genus.";
RL G3 (Bethesda) 1:11-25(2011).
RN [4] {ECO:0000313|EMBL:EJT43128.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IFO 1802 {ECO:0000313|EMBL:EJT43128.1};
RA Cliften P., Hittinger C.T., Wang B., Sudarsanam P., Desikan A., Fulton L.,
RA Fulton B., Majors J., Waterston R., Cohen B.A., Johnston M.;
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:CAI4061803.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IFO1802 {ECO:0000313|EMBL:CAI4061803.1};
RA Byrne P K.;
RL Submitted (OCT-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|RuleBase:RU004020}.
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DR EMBL; OX365902; CAI4061803.1; -; Genomic_DNA.
DR EMBL; AACI03001008; EJT43128.1; -; Genomic_DNA.
DR AlphaFoldDB; J5PMU9; -.
DR STRING; 226230.J5PMU9; -.
DR HOGENOM; CLU_017670_1_0_1; -.
DR Proteomes; UP000002753; Unassembled WGS sequence.
DR Proteomes; UP001162087; Chromosome 7.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR027725; HSF_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10015:SF206; HEAT SHOCK FACTOR PROTEIN; 1.
DR PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR PRINTS; PR00056; HSFDOMAIN.
DR SMART; SM00415; HSF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00434; HSF_DOMAIN; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000002753}.
FT DOMAIN 215..239
FT /note="HSF-type DNA-binding"
FT /evidence="ECO:0000259|PROSITE:PS00434"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 64..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 781..806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 781..798
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 836 AA; 92720 MW; FBAA10317142ED97 CRC64;
MNNVANTGAT NEPNISDASR VEPLPSLNDD DIEKILQPND IFINDRTDAS TTSSTAIEDI
INPSLDPQSV ASPAPSPSFF NNSRKPSTST HLVRRGTPLG IYQTNIYNHN NRENGNSNNT
LLSSKLLTHP PVPYGQNPNL LQQHAVYRAQ TSCGTANTQP RQPTRRYQSH KSRPAFVNKL
WSMLNDDSNA KLIQWAPDGK SFIVTNREEF VHEILPKYFK HSNFASFVRQ LNMYGWHKVQ
DVKSGSIQSS SDDKWQFENE NFIRGREDLL EKIIRQKGSS NNQGSPGGNG SSTNGSNIPM
DNATGVNNSS TNISSSNNFF NNSHLLQGKT LRLMNEAALG DKNDVTAILG ELEQIKYNQI
AISKDLLRIN KDNELLWKEN MMARERHRTQ QQALEKMFRF LTSIVPHLDP KMIMDGLGDS
KNNSENLSGA TNIGLNHDNT GTIDELKSND SFINDDHHPY INITANARNN MSPSNEGSSI
NVSSSNTNSR KKHVDESIKN SNDIINDIIF NTNFANNLTN YSSSNNAGSP LRPYKQRYLL
KNRANSTASS ENSGVTPFNL ESNSDGKISE IPFDGEEDDD TDFKRFTARN PSSQANANSF
DPTRFTMLSD EDLKKDSHAN DTKHDESDLF LGNVHRNIDE QDARLQNLEN MVHILSPGYS
NKPYNNKAAA HTNPNIEGGT SVHSPGFNLQ DYLTGESNSP NSVHSIPSNG SGSTPLPMPN
DNDNEHISTS SSVNADAGEN VTGLTPFLTV DDHTLNDNND EDSASVSPDI KFAATESSKV
NDTLPSFNDH TYSNEAAAAP KNTKKRYVEE IPEPAIVEIQ DPAEYNEQRQ HKRPKK
//
