ID   J5WIH8_9FIRM            Unreviewed;       390 AA.
AC   J5WIH8;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing {ECO:0000313|EMBL:EJU22182.1};
DE            EC=3.1.4.- {ECO:0000313|EMBL:EJU22182.1};
DE            EC=5.1.3.- {ECO:0000313|EMBL:EJU22182.1};
GN   Name=neuC {ECO:0000313|EMBL:EJU22182.1};
GN   ORFNames=HMPREF1143_0780 {ECO:0000313|EMBL:EJU22182.1};
OS   Peptoanaerobacter stomatis.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC   Peptoanaerobacter.
OX   NCBI_TaxID=796937 {ECO:0000313|EMBL:EJU22182.1, ECO:0000313|Proteomes:UP000005244};
RN   [1] {ECO:0000313|EMBL:EJU22182.1, ECO:0000313|Proteomes:UP000005244}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OBRC8 {ECO:0000313|EMBL:EJU22182.1,
RC   ECO:0000313|Proteomes:UP000005244};
RA   Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA   Nelson K.E.;
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJU22182.1}.
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DR   EMBL; ALNK01000023; EJU22182.1; -; Genomic_DNA.
DR   RefSeq; WP_009531152.1; NZ_ALNK01000023.1.
DR   AlphaFoldDB; J5WIH8; -.
DR   PATRIC; fig|796941.3.peg.1320; -.
DR   Proteomes; UP000005244; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR   GO; GO:0006047; P:UDP-N-acetylglucosamine metabolic process; IEA:InterPro.
DR   CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR020004; UDP-GlcNAc_Epase.
DR   InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR   InterPro; IPR029767; WecB-like.
DR   NCBIfam; TIGR03568; NeuC_NnaA; 1.
DR   PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   PANTHER; PTHR43174:SF3; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   Pfam; PF02350; Epimerase_2; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EJU22182.1};
KW   Isomerase {ECO:0000313|EMBL:EJU22182.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005244}.
FT   DOMAIN          24..369
FT                   /note="UDP-N-acetylglucosamine 2-epimerase"
FT                   /evidence="ECO:0000259|Pfam:PF02350"
SQ   SEQUENCE   390 AA;  43729 MW;  A9293CF7529862C8 CRC64;
     MKKIISVLTA TRAEYGLLKP LIKKLSKIEE FDVRIVATGM HLSQEFGLTY KEIEQDGFVI
     DKKIEILLSS DTSSSVSKSM GLAMISFADY FSSLKPNLLI VLGDRYETLA VSLVAMNEKI
     PIAHLYGGEK TEGAIDDVIR HSITKLSYLH FTSTDEYRKR VVQLGEHPNR VFNVGALGIE
     NILNEKLLTK KELEASLNIS LDKKYAIATF HPVTLEDKTA KAQITNLLDV CSEYENINFI
     FTKSNADANG RMINKILDEY EKKADNIYVF TSLGMLRYLS ALKYCSFVIG NSSSGLLEAP
     TFKIPTINIG DRQKGRQKAS SVIDCLPDKS SIQKAIDKAI ENEFIDISKN TVNPYGDGNS
     SDKIIKILKK YLLKENIDLK KSFYDCEVNE
//