ID J5XZK8_9ACTN Unreviewed; 330 AA.
AC J5XZK8;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Phosphate acetyltransferase {ECO:0000256|ARBA:ARBA00021528};
DE EC=2.3.1.8 {ECO:0000256|ARBA:ARBA00012707};
DE AltName: Full=Phosphotransacetylase {ECO:0000256|ARBA:ARBA00031108};
GN Name=pta {ECO:0000313|EMBL:EJU33002.1};
GN ORFNames=HMPREF1155_1038 {ECO:0000313|EMBL:EJU33002.1};
OS Slackia sp. CM382.
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Slackia.
OX NCBI_TaxID=1111137 {ECO:0000313|EMBL:EJU33002.1, ECO:0000313|Proteomes:UP000004399};
RN [1] {ECO:0000313|EMBL:EJU33002.1, ECO:0000313|Proteomes:UP000004399}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM382 {ECO:0000313|EMBL:EJU33002.1,
RC ECO:0000313|Proteomes:UP000004399};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + phosphate = acetyl phosphate + CoA;
CC Xref=Rhea:RHEA:19521, ChEBI:CHEBI:22191, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.1.8;
CC Evidence={ECO:0000256|ARBA:ARBA00000705};
CC -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis;
CC acetyl-CoA from acetate: step 2/2. {ECO:0000256|ARBA:ARBA00004989}.
CC -!- SIMILARITY: Belongs to the phosphate acetyltransferase and
CC butyryltransferase family. {ECO:0000256|ARBA:ARBA00005656}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJU33002.1}.
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DR EMBL; ALNO01000016; EJU33002.1; -; Genomic_DNA.
DR RefSeq; WP_009078754.1; NZ_ALNO01000016.1.
DR AlphaFoldDB; J5XZK8; -.
DR PATRIC; fig|1111137.3.peg.1322; -.
DR Proteomes; UP000004399; Unassembled WGS sequence.
DR GO; GO:0008959; F:phosphate acetyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.10950; -; 1.
DR Gene3D; 3.40.50.10750; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR InterPro; IPR012147; P_Ac_Bu_trans.
DR InterPro; IPR004614; P_AcTrfase.
DR InterPro; IPR042113; P_AcTrfase_dom1.
DR InterPro; IPR042112; P_AcTrfase_dom2.
DR InterPro; IPR002505; PTA_PTB.
DR NCBIfam; TIGR00651; pta; 1.
DR PANTHER; PTHR43356; PHOSPHATE ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43356:SF3; PHOSPHATE ACETYLTRANSFERASE; 1.
DR Pfam; PF01515; PTA_PTB; 1.
DR PIRSF; PIRSF000428; P_Ac_trans; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:EJU33002.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EJU33002.1}.
FT DOMAIN 4..323
FT /note="Phosphate acetyl/butaryl transferase"
FT /evidence="ECO:0000259|Pfam:PF01515"
SQ SEQUENCE 330 AA; 34551 MW; 3CBCA3A7A4948568 CRC64;
MSTFMSDVYS QAKKQKTTIV LPEGEDERTL VAAERILAEG IADLIIIGNQ QAIASSGYDL
SGATVIDNTT DPLRAELAEA LFEIRKAKGM TIEQADALMD DVTYFGTMLL KTGRAQGLVS
GACHPTKDVL SPALRVIKTK PGTKVVSSFF IMEVPNEAYG DDGLMLFSDC AVCIQPNAEE
LSEIAVASAR SFKDLTGAEP RVAMLSHATK GSVIDDDAAK VVEATRLARE KAPGFLIDGE
LQADAAIVQS VGASKAPDSS VAGCANVLVF PDLDAANIGY KLVQRLAGAN AFGPITQGLN
APMNDLSRGC SAEDIVAVVA ITAVQAQGIV
//
