ID J6IWQ8_9RHOB Unreviewed; 298 AA.
AC J6IWQ8;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Putative 3-hydroxyisobutyrate dehydrogenase {ECO:0000313|EMBL:EJW09785.1};
GN ORFNames=A33M_0950 {ECO:0000313|EMBL:EJW09785.1};
OS Rhodovulum sp. PH10.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Rhodovulum.
OX NCBI_TaxID=1187851 {ECO:0000313|EMBL:EJW09785.1, ECO:0000313|Proteomes:UP000002930};
RN [1] {ECO:0000313|EMBL:EJW09785.1, ECO:0000313|Proteomes:UP000002930}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PH10 {ECO:0000313|EMBL:EJW09785.1,
RC ECO:0000313|Proteomes:UP000002930};
RX PubMed=23105089; DOI=10.1128/JB.01695-12;
RA Khatri I., Nupur, Korpole S., Subramanian S., Pinnaka A.K.;
RT "Draft Genome Sequence of Rhodovulum sp. Strain PH10, a Phototrophic
RT Alphaproteobacterium Isolated from a Soil Sample of Mangrove of Namkhana,
RT India.";
RL J. Bacteriol. 194:6363-6363(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJW09785.1}.
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DR EMBL; AKZI01000138; EJW09785.1; -; Genomic_DNA.
DR RefSeq; WP_008390654.1; NZ_AKZI01000138.1.
DR AlphaFoldDB; J6IWQ8; -.
DR STRING; 1187851.A33M_0950; -.
DR PATRIC; fig|1187851.3.peg.3979; -.
DR eggNOG; COG2084; Bacteria.
DR OrthoDB; 9812907at2; -.
DR Proteomes; UP000002930; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000002930}.
FT DOMAIN 12..170
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 174..297
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 180
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 298 AA; 30179 MW; CAA7C7B38C8BB303 CRC64;
MTETGTDDAT AIAFLGLGAM GSRMASNLLK AGHRVTVWNR TPAAAAPLVA AGATPAKSPR
EAAANAAFVL SMVRDDEASR AVWLDDDTGA LDALGRDAVA IECSTVTPDW SIALAQEAAA
RERAFLEAPV VGSRPQAEAA ALIVLAGGEA DTLARARPVL DAMSSAVHHA GAIGAGALLK
LSVNALLGIQ VAAWAELIGF LGRAGLDVAH AVEIIGATPS ASPAGKANAG LMVAKKVAPL
FPVELIRKDL DYALTAAAAT TAGGPSLPLV GAARDVFRRG CEETLGGENM TSVVKLYD
//
