ID J7L506_NOCAA Unreviewed; 464 AA.
AC J7L506;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Major Facilitator Superfamily protein {ECO:0000313|EMBL:AFR06520.1};
GN OrderedLocusNames=B005_4281 {ECO:0000313|EMBL:AFR06520.1};
OS Nocardiopsis alba (strain ATCC BAA-2165 / BE74).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1205910 {ECO:0000313|EMBL:AFR06520.1, ECO:0000313|Proteomes:UP000003779};
RN [1] {ECO:0000313|EMBL:AFR06520.1, ECO:0000313|Proteomes:UP000003779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2165 / BE74 {ECO:0000313|Proteomes:UP000003779};
RX PubMed=23105086; DOI=10.1128/JB.01522-12;
RA Qiao J., Chen L., Li Y., Wang J., Zhang W., Chen S.;
RT "Whole-Genome Sequence of Nocardiopsis alba Strain ATCC BAA-2165,
RT Associated with Honeybees.";
RL J. Bacteriol. 194:6358-6359(2012).
RN [2] {ECO:0000313|Proteomes:UP000003779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2165 / BE74 {ECO:0000313|Proteomes:UP000003779};
RA Qiao J., Chen L., Li Y., Wang J., Zhang W., Chen S.;
RT "Whole-genome sequence of Nocardiopsis alba strain ATCC BAA-2165 associated
RT with honeybees.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003788; AFR06520.1; -; Genomic_DNA.
DR AlphaFoldDB; J7L506; -.
DR STRING; 1205910.B005_4281; -.
DR KEGG; nal:B005_4281; -.
DR PATRIC; fig|1205910.3.peg.4058; -.
DR eggNOG; COG2814; Bacteria.
DR HOGENOM; CLU_034180_11_0_11; -.
DR OrthoDB; 5494559at2; -.
DR Proteomes; UP000003779; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06173; MFS_MefA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR010290; TM_effector.
DR PANTHER; PTHR23513:SF9; ENTEROBACTIN EXPORTER ENTS; 1.
DR PANTHER; PTHR23513; INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR Pfam; PF05977; MFS_3; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003779};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 48..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..432
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 464 AA; 47626 MW; 489E2AA3440BE331 CRC64;
MEPSCGSTGR APGPDTHAPV PAFVKDPVKL STLMVDIGPL RTSREFRIVF VARLVSIFGL
GFAAVALPMQ VYQLTGSSLA VATVHTTSAV SVLTGTIVAG MLADRGDRRR LIVIGRASAV
IGFGALAVNT LTPGEPWLWV IYAAAAFNGF FGSFSAVALQ AAAPGFVPRD KLPAAGALLA
LNGELGSVLA PALGGGIIAL WGMGTNFVIT ALLSLFTTLL VWRLPRLDAP EDGRQQSIAT
ALREGGRFAI GHRVVGPLLL LGLVQMLFAA PQVLINEFTD KVLGGGPGLV GLLYTAPAVG
ALLGSLTSGW AGRAHRTGAL LLTAVTLCGL AVLGLGASTW APFAFMFLAF LGFGQVVEEI
LRYALLQSHT PDRLRGRVNA VWTAQSTVGG SAGALTLGGL APLIGAAGAL MAGGALTIVS
VGALAVAFAG LRTARVLRDP ETLASDGPPV ADADRTTRTD KEKK
//
