ID   J7LHK9_NOCAA            Unreviewed;       834 AA.
AC   J7LHK9;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=DEAD/DEAH box helicase family protein {ECO:0000313|EMBL:AFR11000.1};
GN   OrderedLocusNames=B005_3676 {ECO:0000313|EMBL:AFR11000.1};
OS   Nocardiopsis alba (strain ATCC BAA-2165 / BE74).
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Nocardiopsaceae; Nocardiopsis.
OX   NCBI_TaxID=1205910 {ECO:0000313|EMBL:AFR11000.1, ECO:0000313|Proteomes:UP000003779};
RN   [1] {ECO:0000313|EMBL:AFR11000.1, ECO:0000313|Proteomes:UP000003779}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-2165 / BE74 {ECO:0000313|Proteomes:UP000003779};
RX   PubMed=23105086; DOI=10.1128/JB.01522-12;
RA   Qiao J., Chen L., Li Y., Wang J., Zhang W., Chen S.;
RT   "Whole-Genome Sequence of Nocardiopsis alba Strain ATCC BAA-2165,
RT   Associated with Honeybees.";
RL   J. Bacteriol. 194:6358-6359(2012).
RN   [2] {ECO:0000313|Proteomes:UP000003779}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-2165 / BE74 {ECO:0000313|Proteomes:UP000003779};
RA   Qiao J., Chen L., Li Y., Wang J., Zhang W., Chen S.;
RT   "Whole-genome sequence of Nocardiopsis alba strain ATCC BAA-2165 associated
RT   with honeybees.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|ARBA:ARBA00008708}.
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DR   EMBL; CP003788; AFR11000.1; -; Genomic_DNA.
DR   RefSeq; WP_014913452.1; NC_018524.1.
DR   AlphaFoldDB; J7LHK9; -.
DR   STRING; 1205910.B005_3676; -.
DR   KEGG; nal:B005_3676; -.
DR   PATRIC; fig|1205910.3.peg.3479; -.
DR   eggNOG; COG4581; Bacteria.
DR   HOGENOM; CLU_017075_0_0_11; -.
DR   OrthoDB; 3229913at2; -.
DR   Proteomes; UP000003779; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17921; DEXHc_Ski2; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR021904; DUF3516.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF1; ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF12029; DUF3516; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AFR11000.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003779}.
FT   DOMAIN          39..195
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          247..415
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   834 AA;  93582 MW;  BC138FAA4CC4ED24 CRC64;
     MSLIDALPTE PEPDSLFEAF ALWVEERGLT LYPHQEEALI EVVSGSNVIL NTPTGSGKSL
     VATGALFAAL ARDECAFYTA PIKALVSEKF FDLCKIFGTE NVGMMTGDAS VNADAPIVCC
     TAEVLAQIAL AEGKDADINT VVMDEFHFYA EPDRGWAWQV PLLEMPQAQF LLMSATLGDV
     SRFEEDLEKR TGRSTAVVAS AERPVPLYYD YRVTPLHETL EELLGSGNAP VYIVHFTQAQ
     AVERAQSLTS INMCTKEEKA RIAEEIGDFR FTTRFGRNLS RYVRHGIGVH HAGMLPKYRR
     LVERLAQAGL LKVICGTDTL GVGVNVPIRT VLFTALSKYD GVRVRRLRAR EFHQIAGRAG
     RAGFDTVGNV VAQAPEHVIE NEKALAKAGD DTKKRRKVVR KKAPDGFVSW DEATFRKLID
     AEPEPLNSRF RVSNAMLLSV IARPGNCFTA MKHLLTENHD DRKTQRRHIH EAIAIYRSLL
     DGGIVETLAE PDEQGRTARL TVDLQADFAL NQPLSTFALA ALDLLDVESP TYPLDVLSVV
     ESTLDDPRQI LGAQLNKARG EAVQQMKLDG IEYEERMERL EEVDYPKPLE ELLDHAYEVY
     RRGHPWVGDH PLRPKTIARD MYERAMTFTE YVGHYELARS EGLVLRYLAG AYKALNQTVP
     DDSKTEELRD LIEWLGELVR QVDSSLLDEW ERLTNPEDET EEGHEPEERV RPVTANARAF
     RVLVRNEMFR RVELASRRRY GDLGKLSEDD EWTGEDWAEA VEEYYAEHDE IGTGPDARGP
     KMLLIEEESD VWRVRQVLAD PAGDHDWGIA AEVDLAASDA EGRAVVRVID VDRL
//