ID J7Q3P6_METSZ Unreviewed; 591 AA.
AC J7Q3P6;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:CCJ06134.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:CCJ06134.1};
GN OrderedLocusNames=BN69_0683 {ECO:0000313|EMBL:CCJ06134.1};
OS Methylocystis sp. (strain SC2).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylocystaceae; Methylocystis.
OX NCBI_TaxID=187303 {ECO:0000313|EMBL:CCJ06134.1, ECO:0000313|Proteomes:UP000005263};
RN [1] {ECO:0000313|EMBL:CCJ06134.1, ECO:0000313|Proteomes:UP000005263}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC2 {ECO:0000313|EMBL:CCJ06134.1,
RC ECO:0000313|Proteomes:UP000005263};
RX PubMed=23045511; DOI=10.1128/JB.01446-12;
RA Dam B., Dam S., Kube M., Reinhardt R., Liesack W.;
RT "Complete Genome Sequence of Methylocystis sp. Strain SC2, an Aerobic
RT Methanotroph with High-Affinity Methane Oxidation Potential.";
RL J. Bacteriol. 194:6008-6009(2012).
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DR EMBL; HE956757; CCJ06134.1; -; Genomic_DNA.
DR RefSeq; WP_014890168.1; NC_018485.1.
DR AlphaFoldDB; J7Q3P6; -.
DR STRING; 187303.BN69_0683; -.
DR KEGG; msc:BN69_0683; -.
DR PATRIC; fig|187303.17.peg.745; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_2_5; -.
DR OrthoDB; 9789078at2; -.
DR Proteomes; UP000005263; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 1.10.150.770; -; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:CCJ06134.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:CCJ06134.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 76..185
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 249..538
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 591 AA; 63803 MW; 23889167367682FF CRC64;
MTQTMRDTQP SPRSEGKIGA MLRALFSTSL ALSASRMRLA ALGFLVLYAV IAIKLVYLGF
KPEAATSRRA AAEAVAASRP DIIDRNGEAL ASDVKVMSVF AEPRRIIDKD EATELLTAVL
PGLDARELRE RLGSKKGFVW VKREVTSHQR DEVFHLGLPG VGLIAENKRV YPNGPIGAHV
LGFANVDNQG IAGIEKYIDG QGLADLHGAG FGVTPEELKP VSLSLDIRAT HALRDELEKG
VTHFKAKAGA AAIMDVNTGE VIALASLPDY DPNKPTEALD PLHINRMSVG VYEMGSTFKA
LTIAMALDSG KVNLNSRLDA RGVLSFGRFK IHDYHAQNRA LTLPEVFTYS SNVGTARMAM
GQGVERHKAF LRKMGQLTRM RTELPESAEP IVPKNWGELN TMTIAFGHGL AVAPLQAMMA
VGALMNGGYL ITPTFIKRSE EEAKAGAERV IRPETSEAMR YLMRLNAEIG TARKVNVPGY
YVGGKTGTAE KVVNGHYSKT KLFNTFMAVA PSDKPKYLFL TIMDEPQGLP ETGGYATAAY
NAGQVTGEII ERVGPILGLA PRFEPPHQPF PLLAKLGYGY ANVPARGGGG H
//
