ID J7Q3Y3_METSZ Unreviewed; 227 AA.
AC J7Q3Y3;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN OrderedLocusNames=BN69_1043 {ECO:0000313|EMBL:CCJ06494.1};
OS Methylocystis sp. (strain SC2).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylocystaceae; Methylocystis.
OX NCBI_TaxID=187303 {ECO:0000313|EMBL:CCJ06494.1, ECO:0000313|Proteomes:UP000005263};
RN [1] {ECO:0000313|EMBL:CCJ06494.1, ECO:0000313|Proteomes:UP000005263}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC2 {ECO:0000313|EMBL:CCJ06494.1,
RC ECO:0000313|Proteomes:UP000005263};
RX PubMed=23045511; DOI=10.1128/JB.01446-12;
RA Dam B., Dam S., Kube M., Reinhardt R., Liesack W.;
RT "Complete Genome Sequence of Methylocystis sp. Strain SC2, an Aerobic
RT Methanotroph with High-Affinity Methane Oxidation Potential.";
RL J. Bacteriol. 194:6008-6009(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR EMBL; HE956757; CCJ06494.1; -; Genomic_DNA.
DR RefSeq; WP_014890528.1; NC_018485.1.
DR AlphaFoldDB; J7Q3Y3; -.
DR STRING; 187303.BN69_1043; -.
DR KEGG; msc:BN69_1043; -.
DR PATRIC; fig|187303.17.peg.1135; -.
DR eggNOG; COG0693; Bacteria.
DR HOGENOM; CLU_070319_2_0_5; -.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000005263; Chromosome.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 24..222
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 227 AA; 24551 MW; F209F4933E6A7D48 CRC64;
MKILIVLTSH DKLGDTGEKT GFWLEELVAP YYVFLDAGAE ITLASPKGGQ PPLDPKSSEP
RFQTELTRRF EADEAAKARL ADTARLDSVR QEDFDAVFYP GGHGPMWDLA EDRDSIRLIE
SFVRAGKPIA LVCHAPGVLR HVEGPDGLPL VAGKTVTGFT NGEEEAVGLT HVVPFLVEDE
LQAKGGRFSK AADWAPHVVR DGQLITGQNP ASSDPAARKL VEALSRA
//
