ID J7Q4D7_METSZ Unreviewed; 474 AA.
AC J7Q4D7;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:CCJ07264.1};
GN OrderedLocusNames=BN69_1813 {ECO:0000313|EMBL:CCJ07264.1};
OS Methylocystis sp. (strain SC2).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylocystaceae; Methylocystis.
OX NCBI_TaxID=187303 {ECO:0000313|EMBL:CCJ07264.1, ECO:0000313|Proteomes:UP000005263};
RN [1] {ECO:0000313|EMBL:CCJ07264.1, ECO:0000313|Proteomes:UP000005263}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC2 {ECO:0000313|EMBL:CCJ07264.1,
RC ECO:0000313|Proteomes:UP000005263};
RX PubMed=23045511; DOI=10.1128/JB.01446-12;
RA Dam B., Dam S., Kube M., Reinhardt R., Liesack W.;
RT "Complete Genome Sequence of Methylocystis sp. Strain SC2, an Aerobic
RT Methanotroph with High-Affinity Methane Oxidation Potential.";
RL J. Bacteriol. 194:6008-6009(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; HE956757; CCJ07264.1; -; Genomic_DNA.
DR RefSeq; WP_014891293.1; NC_018485.1.
DR AlphaFoldDB; J7Q4D7; -.
DR STRING; 187303.BN69_1813; -.
DR KEGG; msc:BN69_1813; -.
DR PATRIC; fig|187303.17.peg.1965; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_13_1_5; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000005263; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF15; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
FT DOMAIN 15..448
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 168..381
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 57..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 474 AA; 51665 MW; DC0DB77D31BEDB57 CRC64;
MTRRHIVILL GFAVVAASLA WLVEGRFKWV TPTGTLGDAG PNISDKAPAT TGPIIYYRDP
DGRPSYSSTP KKTSAGKDYL PVRASEDVSF EDKPPAGAAK IGGERRVRFY RHPMGLPDTS
PVPKKDEMGM DYVPVYEDEA ENGATITISP GKLQKTGVRS EPVQRRTLSV PVRATGRIDF
DPRRISIVSL RFEGFIESVG KFAEGDYVRK GQTLMRVYGP NLSSAAAEYV AVLNMRRGGG
IDAQRLEGAK RRLVNLGLDE SAIAAIGRAR SVPRVIAWPA PQDGHVLERA AINGMHAAPG
DMLFRIVDHS LVWVLADLAE RDIALIKPGQ KVDVRPRAYP DRAFKGQVAL IYPHLNMETR
TARVRIELPN PDGLLRGDMY AEVEIAAGGN EKVLTAPESA VIDTGKRQVA IVDKGEGRFE
PREVKIGRRG EGFVEIKSGV SENERVVTTA NFLIDAESNL KAALRALDQG EAGK
//
