ID J7QRW9_METSZ Unreviewed; 1045 AA.
AC J7QRW9;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Acriflavin resistance protein {ECO:0000313|EMBL:CCJ08298.1};
GN OrderedLocusNames=BN69_2847 {ECO:0000313|EMBL:CCJ08298.1};
OS Methylocystis sp. (strain SC2).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylocystaceae; Methylocystis.
OX NCBI_TaxID=187303 {ECO:0000313|EMBL:CCJ08298.1, ECO:0000313|Proteomes:UP000005263};
RN [1] {ECO:0000313|EMBL:CCJ08298.1, ECO:0000313|Proteomes:UP000005263}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC2 {ECO:0000313|EMBL:CCJ08298.1,
RC ECO:0000313|Proteomes:UP000005263};
RX PubMed=23045511; DOI=10.1128/JB.01446-12;
RA Dam B., Dam S., Kube M., Reinhardt R., Liesack W.;
RT "Complete Genome Sequence of Methylocystis sp. Strain SC2, an Aerobic
RT Methanotroph with High-Affinity Methane Oxidation Potential.";
RL J. Bacteriol. 194:6008-6009(2012).
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DR EMBL; HE956757; CCJ08298.1; -; Genomic_DNA.
DR RefSeq; WP_014892324.1; NC_018485.1.
DR AlphaFoldDB; J7QRW9; -.
DR STRING; 187303.BN69_2847; -.
DR KEGG; msc:BN69_2847; -.
DR PATRIC; fig|187303.17.peg.3087; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_5; -.
DR OrthoDB; 9807350at2; -.
DR Proteomes; UP000005263; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF21; MULTIDRUG RESISTANCE PROTEIN MDTB; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 334..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 856..873
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 893..919
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 955..972
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 984..1010
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1021..1045
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1045 AA; 112196 MW; F2737A8FA24C37D1 CRC64;
MNVSAPFIRR PVATSLLAFA VLLFGVMGYL RLPVSPLPQV DFPTIQVTTQ LPGGNPDTIA
SLVTASLERQ FGQIPSLTSM SSQSSFGLSQ ITLQFDLDRN IDAAAQDVQA AINAAASTLP
RNLPYPPVYA KVNPADTPIL TLTLRSKTAT LRDLSDRADT LIAPQLSQVS GVGRVSVQGG
VRPAVRIQAD LGRLAANRIG MEDLRLAIAS ANIAGAKGSL DGSRQSYMLD ANDQILHASQ
YNNIIVAWRN GAPVMLRDVA HVIDGLENAR VGGWHNGEQT VVLDVLRQPG ANIINTVELV
KSELPQIQRA LPAGMSLEIV NDRTVTIRAS IFEVQLTLVI ASALVVLVVL MFLRSWRATI
IAGVSLPLSI IATFAIMWAA GFSLDNLSLM ALTIGTGFIV DDAIVMIENI VRNIEEGKAP
RQAALDGARQ IGFTVVSLTV SLIAVFIPLL FMTGIVGRMF REFALTLTIA VVVSAVISLT
LTPMLCAALL RMAPPHGQSR WETLSLALDR AYQVSLDWAL KRETFMLALT VATLALTIAL
YAVIPKGFLP RQDTGVLSAV MEASSDASFD KMTALQAKIA EEFRRDPDVS GVTSVLGVGP
LNATTNVARL TVMLRPHGER RENAEKIADR LKAAGERTPG VTLYVQPVQD IQITTRPSRS
QFQYTLTAAD AGELLTWSGR LLDQLRMTPG LRNVAAETQE GGLRTLMRID RDKMGRLGIT
AQNVDDALND AFGQRQISMI YTQSNQYRVI LEAAPQYLRD PSALEKLYVA PIGGGPQTPL
ATFARLENLS APLSVAHQDQ FPASTISFDL AEGYSLGDAV KMIANAEAAI GMPSSIVGVF
SADAAEFNKS LASQPWLILA AIVSIYIVLG VLYESFAHPF TVLTTLPSAG VGALLALLAL
HIEMSIVALI GVVLLMGIVK KNAIMMIDFA LDAERDEGLS ARDAIVRACH LRFRPIMMTT
LAALFGALPL ALSHGPGSEL RIPLGVAIIG GLLLSQALTL YTTPVIYLAV ERLRVRLSPP
AQPPAAEEFK PFGQLPKPPT REAAE
//
