ID J7S127_CAEEL Unreviewed; 493 AA.
AC J7S127;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE SubName: Full=CRC domain-containing protein {ECO:0000313|EMBL:CCM09382.1};
GN ORFNames=CELE_ZK287.1 {ECO:0000313|EMBL:CCM09382.1}, ZK287.1
GN {ECO:0000313|EMBL:CCM09382.1, ECO:0000313|WormBase:ZK287.1b};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCM09382.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCM09382.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCM09382.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the lin-54 family.
CC {ECO:0000256|ARBA:ARBA00007267}.
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DR EMBL; BX284605; CCM09382.1; -; Genomic_DNA.
DR RefSeq; NP_001263843.1; NM_001276914.1.
DR AlphaFoldDB; J7S127; -.
DR EPD; J7S127; -.
DR PeptideAtlas; J7S127; -.
DR EnsemblMetazoa; ZK287.1b.1; ZK287.1b.1; WBGene00013962.
DR GeneID; 179356; -.
DR AGR; WB:WBGene00013962; -.
DR WormBase; ZK287.1b; CE47822; WBGene00013962; -.
DR OrthoDB; 2871990at2759; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00013962; Expressed in pharyngeal muscle cell (C elegans) and 3 other cell types or tissues.
DR ExpressionAtlas; J7S127; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016814; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR InterPro; IPR013158; APOBEC_N.
DR InterPro; IPR005172; CRC.
DR InterPro; IPR033467; Tesmin/TSO1-like_CXC.
DR Pfam; PF08210; APOBEC_N; 1.
DR SMART; SM01114; CXC; 1.
DR PROSITE; PS51634; CRC; 1.
PE 1: Evidence at protein level;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteomics identification {ECO:0007829|EPD:J7S127,
KW ECO:0007829|PeptideAtlas:J7S127};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT DOMAIN 65..153
FT /note="CRC"
FT /evidence="ECO:0000259|PROSITE:PS51634"
SQ SEQUENCE 493 AA; 55123 MW; 429E0D959038DE8F CRC64;
MASEMSRANN YCCECVASQG RCSADTCPCV AARKTCDEHC ESTRYRGDCL NQAICKCSCE
VDPAKPAKNA CAKSERCDCL RIKEGCSKLC ACKQICKNKE APKKLAKVAK PTSGCQCAKG
KKQCVKKECA CRTVYGFCSA SCKCGGDCTN GASKFSVPKH VQNCFLEHKH ESSGLIVTLI
GEDYVYRGDF YHESKGEPHV EEQLVAAIYD LISKYTVDLH EIQIFVSKSP CFHQDCEPKC
EVVDECKSNK ACAKLLGLLL SKVRKEIKKV DVKMTVKFLY PHLNRGDLYT KQGILCMLQA
GIKVEPLLMK DWCSIMDWSP HVDHKGDYLQ LWNNHHLDKA VAQSQLFINE CRRALGLSMK
FWVAEIHEIV KDTILHFSDL RTKCGDLNDA LKQLDLTATP HKIRSTPSKR RSFIDLHELR
DKLLRSSSSD GGKKAGSHVE DAQAQAMVAS FCGRSFDDCE TDEIAQRIRR ATANINLEIE
TLMEFLNHKG ALS
//
